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Med Oral Patol Oral Cir Bucal. 2021 Jul 1;26(4):e482-e493. doi: 10.4317/medoral.24337.
Odontogenic cysts and tumours of the jaws represent one of the most prevalent groups of oral-maxillofacial lesions. We aimed to evaluate the clinical and pathological characteristics of a cohort of odontogenic cysts (OC) and odontogenic tumours (OT) of the jaws in a Portuguese population.
This observational retrospective study analysed patients diagnosed with either an OC or OT of the jaws at a central hospital of Oporto, Portugal, between 1988 and 2006. Data collected from patients' files included demographic, clinical, radiological and histopathological information. Recurrence was evaluated using univariate and multivariate analysis.
The sample consisted of 397 patients, 231 males (58.2%) and 166 females (41.8%), with a mean-age of 36.7±17 years. Twenty-seven patients (6.8%) presented with more than one lesion providing a total of 433 lesions. There were 396 (91.5%) OC, mostly represented by radicular cysts (n=257;59.4%), dentigerous cysts (n=79;18.2%), or odontogenic keratocysts (n=50;11.5%). There were 37 (8.5%) OT, mostly represented by ameloblastomas (n=16;3.7%), and odontomas (n=9;2.1%). The most common initial clinical manifestation was swelling (n=224;51.7%). Recurrence was observed in 30 cases (6.9%), mostly in ameloblastomas (n=6;37.5%) and odontogenic keratocysts (n=12;24%). In the multivariate analysis the diagnosis classification of the lesion was the only independent and significant variable related with the recurrence (P=0.04).
Radicular cysts were the most commonly occurring type of OC and ameloblastomas the most commonly occurring OT. Amelobastomas and odontogenic keratocysts were the lesions with the highest rates of recurrence. This large sample provides useful information about the frequency profile and characteristics of OC and OT over a period of 18 years, allowing valuable comparison with data from other countries.
颌骨的牙源性囊肿和肿瘤是口腔颌面最常见的病变之一。我们旨在评估葡萄牙人群中一组颌骨牙源性囊肿（OC）和牙源性肿瘤（OT）的临床和病理特征。
本观察性回顾性研究分析了 1988 年至 2006 年间在葡萄牙波尔图一家中心医院诊断为颌骨 OC 或 OT 的患者。从患者档案中收集的数据包括人口统计学、临床、影像学和组织病理学信息。使用单变量和多变量分析评估复发情况。
该样本由 397 名患者组成，其中 231 名男性（58.2%）和 166 名女性（41.8%），平均年龄为 36.7±17 岁。27 名患者（6.8%）存在一种以上病变，共有 433 处病变。有 396 例（91.5%）OC，主要由根尖囊肿（n=257；59.4%）、含牙囊肿（n=79；18.2%）或牙源性角化囊肿（n=50；11.5%）组成。有 37 例（8.5%）OT，主要由成釉细胞瘤（n=16；3.7%）和牙瘤（n=9；2.1%）组成。最常见的初始临床表现为肿胀（n=224；51.7%）。30 例（6.9%）观察到复发，主要见于成釉细胞瘤（n=6；37.5%）和牙源性角化囊肿（n=12；24%）。在多变量分析中，病变的诊断分类是与复发相关的唯一独立和显著变量（P=0.04）。
根尖囊肿是最常见的 OC 类型，成釉细胞瘤是最常见的 OT 类型。成釉细胞瘤和牙源性角化囊肿是复发率最高的病变。这个大样本提供了 18 年来关于 OC 和 OT 频率分布和特征的有用信息，使其能够与其他国家的数据进行有价值的比较。
