是否有适合于严格血糖控制的即时血糖仪？在重症监护病房中评估一种家用和四种医院用血糖仪。

Is there a suitable point-of-care glucose meter for tight glycemic control? Evaluation of one home-use and four hospital-use meters in an intensive care unit.

机构信息

Department of Clinical Chemistry and Hematology, Meander Medical Center, Amersfoort, The Netherlands.

出版信息

Clin Chem Lab Med. 2012 Nov;50(11):1985-92. doi: 10.1515/cclm-2012-0104.

DOI:10.1515/cclm-2012-0104

PMID:22718643

Abstract

BACKGROUND

Implementation of tight glycemic control (TGC) and avoidance of hypoglycemia in intensive care unit (ICU) patients require frequent analysis of blood glucose. This can be achieved by accurate point-of-care (POC) hospital-use glucose meters. In this study one home-use and four different hospital-use POC glucose meters were evaluated in critically ill ICU patients.

METHODS

All patients (n = 80) requiring TGC were included in this study. For each patient three to six glucose measurements (n = 390) were performed. Blood glucose was determined by four hospital-use POC glucose meters, Roche Accu-Check Inform II System, HemoCue Glu201DM, Nova StatStrip, Abbott Precision Xceed Pro, and one home-use POC glucose meter, Menarini GlucoCard Memory PC. The criteria described in ISO 15197, Dutch TNO quality guideline and in NACB/ADA-2011 were applied in the comparisons.

RESULTS

According to the ISO 15197, the percentages of the measured values that fulfilled the criterion were 99.5% by Roche, 95.1% by HemoCue, 91.0% by Nova, 96.6% by Abbott, and 63.3% by Menarini. According to the TNO quality guideline these percentages were 96.1% , 91.0% , 81.8% , 94.2% , and 47.7% , respectively. Application of the NACB/ADA guideline resulted in percentages of 95.6%, 89.2%, 77.9%, 93.4%, and 45.4%, respectively.

CONCLUSIONS

When ISO 15197 was applied, Roche, HemoCue and Abbott fulfilled the criterion in this patient population, whereas Nova and Menarini did not. However, when TNO quality guideline and NACB/ADA 2011 guideline were applied only Roche fulfilled the criteria.

摘要

背景

在重症监护病房（ICU）患者中实施严格的血糖控制（TGC）和避免低血糖需要频繁分析血糖。这可以通过准确的即时检测（POC）医院使用血糖仪来实现。在这项研究中，评估了一种家用和四种不同的医院使用 POC 血糖仪在危重症 ICU 患者中的应用。

方法

所有需要 TGC 的患者（n=80）均纳入本研究。每位患者进行 3 至 6 次血糖测量（n=390）。使用四种医院使用的 POC 血糖仪，罗氏 Accu-Check Inform II 系统、海莫库 Glu201DM、诺华 StatStrip、雅培 Precision Xceed Pro，以及一种家用 POC 血糖仪，美纳里尼 GlucoCard Memory PC，检测血糖。比较时应用了 ISO 15197、荷兰 TNO 质量指南和 NACB/ADA-2011 中描述的标准。

结果

根据 ISO 15197，罗氏符合标准的测量值百分比为 99.5%，海莫库为 95.1%，诺华为 91.0%，雅培为 96.6%，美纳里尼为 63.3%。根据 TNO 质量指南，这些百分比分别为 96.1%、91.0%、81.8%、94.2%和 47.7%。应用 NACB/ADA 指南的结果分别为 95.6%、89.2%、77.9%、93.4%和 45.4%。