Medical Oncology Service, Hospital General Universitario, Valencia, Spain.
Clin Transl Oncol. 2012 Jul;14(7):545-50. doi: 10.1007/s12094-012-0839-6.
High-grade gliomas are an infrequent disease diagnosed usually in the fifth or sixth decade. Careful histopathological diagnosis is essential because tumour grade and type condition the treatment. Magnetic resonance with gadolinium is considered the standard radiologic exploration and should be followed by tissue sampling. Treatment of these patients should be decided in a multidisciplinary committee. Surgery, radiotherapy and chemotherapy are the basis of patients' treatment, with the best results obtained when the three of them can be used.
高级别胶质瘤是一种罕见疾病,通常在第五或第六个十年被诊断出来。仔细的组织病理学诊断是必不可少的,因为肿瘤的分级和类型决定了治疗方法。钆增强磁共振被认为是标准的影像学检查,随后应进行组织取样。这些患者的治疗应在多学科委员会中决定。手术、放疗和化疗是患者治疗的基础,当这三种方法可以联合使用时,可以获得最佳效果。