Department of Internal Medicine 2, Caritaskrankenhaus Bad Mergentheim, Academic Teaching Hospital University of Würzburg, Bad Mergentheim, Germany.
Ultraschall Med. 2012 Jul;33 Suppl 1:S39-47. doi: 10.1055/s-0032-1312895. Epub 2012 Jun 21.
The focus of this article is the emergent and potential indications of contrast-enhanced ultrasound (CEUS). Emergent applications of CEUS techniques include extravascular and intracavitary contrast-enhanced ultrasound, quantitative assessment of microvascular circulation for tumor response assessment, and tumor characterization using dynamic contrast-enhanced ultrasound (DCE-US). Potential indications for microbubble agents include novel molecular imaging and drug and gene delivery techniques, which have been successfully tested in animal models. "Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Non-Liver Guidelines 2011" which focus more on established applications are published in the same supplement to Ultraschall in der Medizin (European Journal of Ultrasound).
本文的重点是新兴的和潜在的超声造影(CEUS)应用。CEUS 技术的紧急应用包括血管外和腔内超声造影、肿瘤反应评估的微血管循环的定量评估以及动态对比增强超声(DCE-US)的肿瘤特征描述。微泡造影剂的潜在适应证包括新型分子成像以及药物和基因传递技术,这些技术已经在动物模型中得到了成功的验证。更侧重于已确立应用的“欧洲超声医学和生物学联合会(EFSUMB)非肝脏指南 2011 年评论和说明”发表在 Ultraschall in der Medizin(《欧洲超声杂志》)的同一增刊上。