Clinical Microbiology & Public Health Laboratory, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Department of Histopathology, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
J Med Microbiol. 2012 Oct;61(Pt 10):1473-1475. doi: 10.1099/jmm.0.044412-0. Epub 2012 Jun 21.
Sweet's syndrome or acute febrile neutrophilic dermatosis has been associated with underlying infection, malignancy, inflammatory disease and certain medications. The infection agents associated with this include Streptococcus species, Yersinia species, Chlamydia species, Salmonella species and Helicobacter pylori. We report a case of Sweet's syndrome in a 73-year-old woman following a 2 week course of severe gastroenteritis caused by Campylobacter species. Histological examination of skin lesions showed marked inflammatory infiltrate throughout the dermis, composed of neutrophils and histiocytes. The patient was successfully treated with topical and systemic steroids. To date, this is the first case of Sweet's syndrome to be reported linked to Campylobacter species to our knowledge.
Sweet 综合征或急性发热性嗜中性皮病与潜在感染、恶性肿瘤、炎症性疾病和某些药物有关。与这种疾病相关的感染因子包括链球菌属、耶尔森菌属、衣原体属、沙门氏菌属和幽门螺杆菌。我们报告了一例 73 岁女性的 Sweet 综合征病例,该患者在两周的弯曲杆菌属引起的严重胃肠炎后出现这种情况。皮肤病变的组织学检查显示真皮内有明显的炎症浸润,由中性粒细胞和组织细胞组成。该患者经局部和全身类固醇治疗成功。据我们所知,这是首例与弯曲杆菌属相关的 Sweet 综合征病例。