Pult Heiko, Riede-Pult Britta H, Purslow Christine
Dr. Heiko Pult-Optometry & Vision Research, Weinheim, Germany.
Optom Vis Sci. 2012 Jul;89(7):E1035-41. doi: 10.1097/OPX.0b013e31825c3479.
To assess the warming and humidifying effect and ocular safety of the Blephasteam® eyelid-warming device vs. warm and moist compresses in healthy volunteers.
Twenty subjects (8 females, 12 males; mean age 39.2 years) were included in the study. Temperature and relative humidity were measured over a period of 10 min at the lower eyelid margin of one randomly selected eye during application of the Blephasteam device and, 1 h later, during application of warm compresses (in a randomized order). Ocular signs and visual acuity were assessed before and after each application.
The mean duration of warming (temperature ≥38°C) was significantly longer with Blephasteam than with compresses (7.5 vs. 1.0 min; p < 0.01). There was no significant difference between treatments in the duration of 100% relative humidity. Compared with pretreatment values, visual acuity significantly improved after Blephasteam treatment (p < 0.05) but significantly decreased after treatment with compresses (p < 0.05). Limbal redness, eyelid redness, and corneal staining scores all improved significantly after Blephasteam treatment (p < 0.05 for all). Ocular signs did not change after compress treatment except conjunctival redness, which was significantly increased (p = 0.01 vs. pretreatment).
The Blephasteam eyelid-warming device appeared to provide more effective warming than warm and moist compresses in a group of healthy volunteers. Visual acuity, limbal redness, and eyelid redness were improved after Blephasteam use but not after treatment with compresses.
评估Blephasteam®眼睑加热装置与温热湿敷对健康志愿者的温热加湿效果及眼部安全性。
本研究纳入20名受试者（8名女性，12名男性；平均年龄39.2岁）。在随机选择的一只眼睛的下眼睑边缘，分别在使用Blephasteam装置期间及1小时后使用温热湿敷时（顺序随机），测量10分钟内的温度和相对湿度。每次使用前后评估眼部体征和视力。
Blephasteam的平均升温持续时间（温度≥38°C）显著长于湿敷（7.5分钟对1.0分钟；p<0.01）。两种治疗方法在100%相对湿度持续时间上无显著差异。与治疗前值相比，Blephasteam治疗后视力显著提高（p<0.05），而湿敷治疗后视力显著下降（p<0.05）。Blephasteam治疗后角膜缘充血、眼睑充血和角膜染色评分均显著改善（均p<0.05）。湿敷治疗后除结膜充血显著增加外（与治疗前相比p = 0.01），眼部体征无变化。
在一组健康志愿者中，Blephasteam眼睑加热装置似乎比温热湿敷提供更有效的升温。使用Blephasteam后视力、角膜缘充血和眼睑充血得到改善，但湿敷治疗后未改善。
