Bzovey Brandon, Ngo William
Centre for Ocular Research & Education, School of Optometry & Vision Science University of Waterloo, Waterloo, Ontario, Canada.
School of Optometry & Vision Science, University of Waterloo, Waterloo, Ontario, Canada.
Clin Optom (Auckl). 2022 Aug 5;14:133-147. doi: 10.2147/OPTO.S350186. eCollection 2022.
Meibomian gland dysfunction (MGD) is characterized by the obstruction and/or inflammation of the meibomian glands that result in decreased and altered meibum secretion. This results in deficiencies in the tear film lipid layer which contributes to increased evaporation and destabilization of the tear film. One of the mainstay therapies for MGD is medical devices that apply heat and/or pressure to the eyelids and promote the liquification and outflow of meibum into the tear film. Over the past two decades, there have been a surge of interest in diagnosing and managing MGD. As a result, numerous medical devices have been developed and each have their own unique approach to treating MGD. This narrative review was conducted to summarize the current state of knowledge on eyelid warming devices, specifically warm eye coverings, devices that direct heat and/or pressure to the eyelids, moisture chamber goggles, and light-based therapy. This review summarized 58 human clinical studies and found that most eyelid warming devices were efficacious in improving signs and symptoms in a wide range of MGD severities and were generally safe to use.
睑板腺功能障碍（MGD）的特征是睑板腺阻塞和/或炎症，导致睑脂分泌减少和改变。这会导致泪膜脂质层缺乏，进而导致泪膜蒸发增加和不稳定。MGD的主要治疗方法之一是使用医疗器械对眼睑施加热量和/或压力，促进睑脂液化并流入泪膜。在过去二十年中，人们对MGD的诊断和管理兴趣激增。因此，已经开发出许多医疗器械，每种器械都有其独特的治疗MGD的方法。本叙述性综述旨在总结眼睑加热装置的当前知识状态，特别是暖眼罩、直接对眼睑施加热量和/或压力的装置、保湿室护目镜和光疗法。该综述总结了58项人体临床研究，发现大多数眼睑加热装置在改善各种严重程度的MGD的体征和症状方面有效，并且通常使用安全。
