Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds General Infirmary, Clarendon Wing Level A, Great George Street, LS1 3EX, Leeds, West Yorkshire, UK.
Int Orthop. 2012 Aug;36(8):1701-7. doi: 10.1007/s00264-012-1572-z. Epub 2012 May 22.
The aim of this study was to evaluate the safety and efficiency, as well as the incorporation characteristics of a specific type of xenograft used for iliac crest defects post-harvesting tri-cortical iliac crest bone graft.
Sixteen patients diagnosed with chronic anterior pelvic pain were operated for pubic symphysis fusion. The tri-cortical graft harvested from the iliac crest was inserted into the pubic symphysis and compressed with a reconstruction plate. The defect in the iliac crest was filled with a block of cancellous bovine substitute (Tutobone®). The length of iliac crest defect, time to fusion of pubic symphysis, time to incorporation of the graft and complications were recorded. The postoperative pain and patients' satisfaction were evaluated.
The median age of patients was 36.5 years (range 27-75). Fusion was obtained in 15 patients (94 %). The median time to fusion was four months (range three to seven). The length of the iliac crest bone defect ranged from 40 to 70 mm. Integration of the bovine substitute was achieved in 15 patients (94 %) over a median period of three months (range two to six). The postoperative median pain score was 2 (range 1-5). Twelve patients (75 %) reported good satisfaction. No major complications or allergic reactions were observed.
The xenograft used in this study provided a safe and effective method of reconstruction of iliac crest donor site defects. It has satisfactory incorporation, high biocompatibility and no signs of inflammatory reactions. This new technique is simple and easily reproducible in routine clinical practice.
本研究旨在评估特定类型异种移植物用于髂嵴骨采集后三皮质髂嵴骨移植的安全性和有效性,以及其植入特征。
16 例慢性骨盆前痛患者接受耻骨联合融合手术。从髂嵴采集的三皮质移植物插入耻骨联合并用重建板加压。髂嵴缺损用松质牛替代物(Tutobone®)填充。记录髂嵴缺损的长度、耻骨联合融合时间、移植物植入时间和并发症。评估术后疼痛和患者满意度。
患者的中位年龄为 36.5 岁(范围 27-75 岁)。15 例(94%)患者融合。融合的中位时间为 4 个月(范围 3-7 个月)。髂嵴骨缺损长度为 40-70mm。牛替代物的中位植入时间为 3 个月(范围 2-6 个月),15 例(94%)患者达到了整合。术后中位疼痛评分为 2 分(范围 1-5 分)。12 例(75%)患者报告满意度良好。未观察到主要并发症或过敏反应。
本研究中使用的异种移植物为髂嵴供体部位缺损的重建提供了一种安全有效的方法。它具有良好的植入性、高生物相容性,无炎症反应迹象。这种新技术在常规临床实践中简单且易于复制。