[昆山地区人群中变应性鼻炎相关抗原的调查]
[Investigation on the antigens responsible for allergic rhinitis occurred in the population of Kunshan district].
作者信息
Du Jihong, Ma Xinrui, Wang Jianzhong, Deng Jianhua
机构信息
Department of Otolaryngology, the First People' Hospital of Kunshan, Kunshan, 215300, China.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Apr;26(8):370-1.
OBJECTIVE
To investigate the distribution and descriptions of the common antigens of allergic rhinitis occurred in the population of Kunshan district so as to provide evidence for clinical diagnosis,treatment and prevention.
METHOD
Eight hundred and twenty allergic rhinitis patients were examined skin prick test (SPT) with 18 kinds of antigen extract of allergic rhinitis.
RESULT
Six hundred and ninety-four (84.6%) cases were detected at least one antigen, 581 (83.7%) cases were detected two or more antigens. The most common antigens among all the positive cases of skin prick tests were dust mite 492 (70.9%), house dust mite 473 (68.2%), crab 32 (4.5%) and egg white 26 (3.7%).
CONCLUSION
Mite, crab and egg white are the most common antigens of allergic rhinitis in Kunshan. SPT is important for the diagnosis, treatment and prevention.
目的
调查昆山地区人群中变应性鼻炎常见抗原的分布及特征，为临床诊断、治疗及预防提供依据。
方法
采用18种变应性鼻炎抗原提取物对820例变应性鼻炎患者进行皮肤点刺试验（SPT）。
结果
694例（84.6%）患者至少检测出一种抗原，581例（83.7%）患者检测出两种或以上抗原。皮肤点刺试验所有阳性病例中最常见的抗原为尘螨492例（70.9%）、屋尘螨473例（68.2%）、蟹32例（4.5%）和蛋清26例（3.7%）。
结论
螨、蟹和蛋清是昆山地区变应性鼻炎最常见的抗原。皮肤点刺试验对诊断、治疗及预防具有重要意义。
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