Department of Pediatrics, University of Utah, Salt Lake City, Utah 84108, USA.
Pediatrics. 2012 Jul;130(1):e16-24. doi: 10.1542/peds.2012-0127. Epub 2012 Jun 25.
Febrile infants in the first 90 days may have life-threatening serious bacterial infection (SBI). Well-appearing febrile infants with SBI cannot be distinguished from those without by examination alone. Variation in care resulting in both undertreatment and overtreatment is common.
We developed and implemented an evidence-based care process model (EB-CPM) for the management of well-appearing febrile infants in the Intermountain Healthcare System. We report an observational study describing changes in (1) care delivery, (2) outcomes of febrile infants, and (3) costs before and after implementation of the EB-CPM in a children's hospital and in regional medical centers.
From 2004 through 2009, 8044 infants had 8431 febrile episodes, resulting in medical evaluation. After implementation of the EB-CPM in 2008, infants in all facilities were more likely to receive evidence-based care including appropriate diagnostic testing, determination of risk for SBI, antibiotic selection, decreased antibiotic duration, and shorter hospital stays (P < .001 for all). In addition, more infants had a definitive diagnosis of urinary tract infection or viral illness (P < .001 for both). Infant outcomes improved with more admitted infants positive for SBI (P = .011), and infants at low risk for SBI were more often managed without antibiotics (P < .001). Although hospital admissions were shortened by 27%, there were no cases of missed SBI. Health Care costs were also reduced, with the mean cost per admitted infant decreasing from $7178 in 2007 to $5979 in 2009 (-17%, P < .001).
The EB-CPM increased evidence-based care in all facilities. Infant outcomes improved and costs were reduced, substantially improving value.
90 天内发热的婴儿可能患有危及生命的严重细菌性感染(SBI)。仅通过检查无法区分有 SBI 的表现良好的发热婴儿和无 SBI 的发热婴儿。由于护理的差异,导致过度治疗和治疗不足的情况很常见。
我们为 Intermountain Healthcare System 中表现良好的发热婴儿开发并实施了一种基于证据的护理流程模型(EB-CPM)。我们报告了一项观察性研究,描述了在一家儿童医院和区域医疗中心实施 EB-CPM 前后(1)护理提供方式的变化,(2)发热婴儿的结局,以及(3)成本的变化。
2004 年至 2009 年期间,有 8044 名婴儿发生了 8431 次发热事件,导致进行了医学评估。在 2008 年实施 EB-CPM 后,所有设施中的婴儿更有可能接受基于证据的护理,包括进行适当的诊断性检查、确定 SBI 风险、选择抗生素、缩短抗生素疗程和缩短住院时间(所有 P <.001)。此外,更多的婴儿被确诊为尿路感染或病毒性疾病(两者均 P <.001)。患有 SBI 的婴儿入院率更高(P =.011),SBI 风险低的婴儿更常无需使用抗生素治疗(P <.001),因此婴儿的结局得到了改善。尽管住院时间缩短了 27%,但没有漏诊 SBI 的情况。医疗保健成本也有所降低,每例住院婴儿的平均费用从 2007 年的 7178 美元降至 2009 年的 5979 美元(降低 17%,P <.001)。
EB-CPM 增加了所有设施的基于证据的护理。婴儿的结局得到改善,成本降低,大大提高了价值。