Pavliuk Iu V, Bogatskii M A, Orlova N V, Anakhova V A
Antibiotiki. 1979 Oct;24(10):723-7.
The effect of phosphorus on biosynthesis of polymyxin B by B. polymyxa 1538 was studied and its optimal concentration in the synthetic and two complex media was determined. Correlation between the culture growth and consumption of the main components, on the one hand, and concentration of phosphorus in the medium, on the other hand, was found. It was shown that the effect of phosphorus on biosynthesis of polymyxin B did not depend on the carbon source in the medium and aeration conditions.
研究了磷对多粘芽孢杆菌1538合成多粘菌素B的影响,并确定了其在合成培养基和两种复合培养基中的最佳浓度。发现了一方面培养物生长和主要成分消耗与另一方面培养基中磷浓度之间的相关性。结果表明,磷对多粘菌素B生物合成的影响不取决于培养基中的碳源和通气条件。