Lima de Araújo L, Maciel Barbosa J, Gomes Ribeiro A P, Oliveira dos Santos A C, Pedrosa F
Clinical Nutrition by the Residency Program in Nutrition at the Institute of Integrative Medicine Professor Fernando Figueira. IMIP, Brazil.
Nutr Hosp. 2012 Mar-Apr;27(2):496-503. doi: 10.1590/S0212-16112012000200022.
The prevalence of malnutrition upon diagnosis, together with reduced food intake secondary to disease and treatment, make the periodic assessment of nutritional status (including the intake of antioxidant nutrients) of considerable importance to the follow up of patients with cancer.
Assess the nutritional status and frequency of inadequate vitamin C levels among children and adolescents with cancer at the beginning of treatment and determine associated factors.
A cross-sectional study was carried out with 30 patients under 18 years. Nutritional status was assessed using laboratory methods and anthropometric measurements. Vitamin C adequacy was assessed through its serum concentration and dietary intake.
In the sample, 10% were short for their age and 13.3% were underweight. The triceps skinfold measurement revealed fat depletion in 68% and the arm muscle circumference measurement revealed muscle depletion in 32.0%. Seventy percent of the patients had vitamin C deficiency and had greater weight loss, lower Z scores for all anthropometric indicators analyzed, lower serum albumin and higher C-reactive protein than those without vitamin C deficiency, but these differences were not statistically significant.
Children with cancer may have nutritional deficits upon diagnosis. Further studies are needed on the association between serum levels of antioxidant and nutritional status in order to offer safe, effective nutritional support.
确诊时营养不良的患病率，以及疾病和治疗导致的食物摄入量减少，使得定期评估营养状况（包括抗氧化营养素的摄入量）对于癌症患者的随访至关重要。
评估癌症儿童和青少年在治疗开始时的营养状况以及维生素C水平不足的频率，并确定相关因素。
对30名18岁以下患者进行了横断面研究。使用实验室方法和人体测量学评估营养状况。通过血清浓度和饮食摄入量评估维生素C充足情况。
在样本中，10%的患者年龄别身高低于正常，13.3%的患者体重不足。三头肌皮褶测量显示68%的患者脂肪消耗，上臂肌肉周长测量显示32.0%的患者肌肉消耗。70%的患者存在维生素C缺乏，与无维生素C缺乏的患者相比，体重减轻更多，所有分析的人体测量指标的Z评分更低，血清白蛋白更低，C反应蛋白更高，但这些差异无统计学意义。
癌症儿童在确诊时可能存在营养缺乏。需要进一步研究抗氧化剂血清水平与营养状况之间的关联，以便提供安全、有效的营养支持。
