临床分离的拟茎点霉属的分子鉴定及抗真菌药物的体外反应
Molecular identification and in vitro response to antifungal drugs of clinical isolates of Exserohilum.
机构信息
Mycology Unit, Medical School and IISPV, Universitat Rovira i Virgili, Reus, Spain.
出版信息
Antimicrob Agents Chemother. 2012 Sep;56(9):4951-4. doi: 10.1128/AAC.00488-12. Epub 2012 Jun 25.
Abstract
Exserohilum is an agent of human and animal mycoses. Although classification has been based on a few subtle morphological differences, three species of clinical interest have been traditionally accepted. In this study, by using a multigene sequence analysis, we have demonstrated that Exserohilum longirostratum and E. mcginnisii are probable synonyms of E. rostratum. The isolates tested were mainly from the nasal region. Antifungal susceptibility testing demonstrated high activity of the eight agents tested against this fungus.
摘要
棘壳孢属是人类和动物真菌感染的病原体。尽管传统上基于一些细微的形态差异进行分类，但已公认有三种棘壳孢属种与临床相关。在这项研究中，我们通过多基因序列分析表明，长喙棘壳孢菌和麦氏棘壳孢菌可能是喙棘壳孢菌的同义词。测试的分离株主要来自鼻腔区域。抗真菌药敏试验表明，测试的 8 种药物对该真菌均具有高度活性。
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