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儿童常见先天性心脏病术后心脏传导阻滞:KID 数据库研究结果。

Postoperative heart block in children with common forms of congenital heart disease: results from the KID Database.

机构信息

Heart Institute, Cincinnati Children's Hospital of Cincinnati, Cincinnati, OH 45229, USA.

出版信息

J Cardiovasc Electrophysiol. 2012 Dec;23(12):1349-54. doi: 10.1111/j.1540-8167.2012.02385.x. Epub 2012 Jun 26.

Abstract

INTRODUCTION

Cardiac conduction system injury is a cause of postoperative cardiac morbidity following repair of congenital heart disease (CHD). The national occurrence of postoperative complete heart block (CHB) following surgical repair of CHD is unknown. We sought to describe the occurrence of and costs related to postoperative CHB following surgical repair of common forms of CHD using a large national database.

METHODS AND RESULTS

Retrospective, observational analysis performed over a 10-year period (2000-2009) using the Kids' Inpatient Database (KID). Visits for patients ≤24 months of age were identified who underwent surgical repair of ventricular septal defects (VSD), atrioventricular canal defects (AVC), and tetralogy of Fallot (TOF). Patients were identified who were diagnosed with postoperative CHB, further identifying those requiring a new pacemaker placement during the same hospitalization. Costs associated with visits were calculated. There were 16,105 surgical visits: 7,146 VSD, 3,480 AVC, and 5,480 TOF. There was a decrease in postoperative mortality (P = 0.0001) with no significant change in postoperative CHB. Hospital stay and cost were higher with CHB and placement of a permanent pacemaker. Repair of AVC (OR 1.77; [1.32-2.38]) was associated with a higher rate of postoperative CHB. Length of hospital stay and total cost were significantly increased with the development of postoperative CHB and increased further with placement of a permanent pacemaker.

CONCLUSION

There has been little change over time in the frequency of postoperative CHB in patients undergoing repair of VSD, AVC, and TOF. Postoperative CHB results in major added cost to the healthcare system.

摘要

简介

心脏传导系统损伤是先天性心脏病(CHD)修复术后心脏发病率的一个原因。全国范围内,CHD 手术后完全性心脏阻滞(CHB)的发生率尚不清楚。我们旨在使用大型国家数据库描述常见类型 CHD 手术后 CHB 的发生情况及其相关费用。

方法和结果

对 Kid's Inpatient Database(KID)进行了为期 10 年(2000-2009 年)的回顾性观察性分析。确定了年龄≤24 个月的患者,这些患者接受了室间隔缺损(VSD)、房室管缺损(AVC)和法洛四联症(TOF)的手术修复。确定了术后患有 CHB 的患者,并进一步确定了在同一住院期间需要新起搏器植入的患者。计算了与就诊相关的费用。共有 16,105 例手术就诊:7,146 例 VSD、3,480 例 AVC 和 5,480 例 TOF。术后死亡率降低(P=0.0001),但 CHB 术后无显著变化。CHB 和永久性起搏器植入会导致住院时间和费用增加。AVC 修复(OR 1.77;[1.32-2.38])与更高的术后 CHB 发生率相关。发生术后 CHB 会显著增加住院时间和总费用,而永久性起搏器的植入则会进一步增加。

结论

VSD、AVC 和 TOF 修复术后 CHB 的频率在过去的时间里变化不大。术后 CHB 会给医疗保健系统带来巨大的额外成本。

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