• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

金纳米笼的 pH 响应型近红外增强药物释放对癌细胞具有高效性。

pH-responsive NIR enhanced drug release from gold nanocages possesses high potency against cancer cells.

机构信息

Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun, Jilin, 130022, P. R. China.

出版信息

Chem Commun (Camb). 2012 Aug 7;48(61):7640-2. doi: 10.1039/c2cc33543c. Epub 2012 Jun 27.

DOI:10.1039/c2cc33543c
PMID:22735385
Abstract

We report a smart therapeutic nanoplatform based on Fe(3)O(4)@CaP capped gold nanocages, which integrates magnetic targeting, photothermal therapy and chemotherapy for killing cancer cells. Combining photothermal- and chemo-therapy results in a synergistic effect in cancer treatment.

摘要

我们报道了一种基于 Fe(3)O(4)@CaP 包覆的金纳米笼的智能治疗性纳米平台，该平台集成了磁性靶向、光热治疗和化学治疗，用于杀死癌细胞。光热治疗和化疗相结合在癌症治疗中具有协同作用。

相似文献

1
pH-responsive NIR enhanced drug release from gold nanocages possesses high potency against cancer cells.金纳米笼的 pH 响应型近红外增强药物释放对癌细胞具有高效性。
Chem Commun (Camb). 2012 Aug 7;48(61):7640-2. doi: 10.1039/c2cc33543c. Epub 2012 Jun 27.
2
pH-triggered blooming of 'nano-flowers' for tumor intracellular drug delivery.pH 触发的“纳米花”绽放用于肿瘤细胞内药物递送。
Chem Commun (Camb). 2012 Aug 21;48(65):8129-31. doi: 10.1039/c2cc34225a. Epub 2012 Jul 10.
3
A multi-stimuli responsive gold nanocage-hyaluronic platform for targeted photothermal and chemotherapy.一种用于靶向光热和化疗的多刺激响应金纳米笼-透明质酸平台。
Biomaterials. 2014 Dec;35(36):9678-88. doi: 10.1016/j.biomaterials.2014.08.013. Epub 2014 Aug 28.
4
Multifunctional mesoporous silica-coated graphene nanosheet used for chemo-photothermal synergistic targeted therapy of glioma.介孔硅包覆的石墨烯纳米片用于脑胶质瘤的化学-光热协同靶向治疗。
J Am Chem Soc. 2013 Mar 27;135(12):4799-804. doi: 10.1021/ja312221g. Epub 2013 Mar 15.
5
An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.一种基于影像引导的协同光动力/光热/化疗平台，具有 pH/温度响应性药物释放功能。
Biomaterials. 2015 Sep;63:115-27. doi: 10.1016/j.biomaterials.2015.05.016. Epub 2015 May 23.
6
Magnetocaloric effect in magnetothermally-responsive nanocarriers for hyperthermia-triggered drug release.磁热疗触发药物释放的磁热响应纳米载体中的磁热效应。
Nanotechnology. 2012 Dec 21;23(50):505706. doi: 10.1088/0957-4484/23/50/505706. Epub 2012 Nov 26.
7
Intracellular fluorescent thermometry and photothermal-triggered drug release developed from gold nanoclusters and doxorubicin dual-loaded liposomes.由金纳米团簇和阿霉素双负载脂质体开发的细胞内荧光测温法及光热触发药物释放
Chem Commun (Camb). 2014 Feb 14;50(13):1546-8. doi: 10.1039/c3cc47981a.
8
Photothermally controlled drug release system with high dose loading for synergistic chemo-photothermal therapy of multidrug resistance cancer.光热控制的高载药量药物释放系统用于协同化疗-光热治疗多药耐药性癌症。
Colloids Surf B Biointerfaces. 2019 Mar 1;175:239-247. doi: 10.1016/j.colsurfb.2018.11.088. Epub 2018 Dec 5.
9
pH-responsive assembly of gold nanoparticles and "spatiotemporally concerted" drug release for synergistic cancer therapy.pH 响应性金纳米粒子组装和“时空协同”药物释放用于协同癌症治疗。
ACS Nano. 2013 Apr 23;7(4):3388-402. doi: 10.1021/nn400223a. Epub 2013 Apr 8.
10
A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance.一种 pH 响应介孔硅纳米粒子的多药物递送系统，用于克服多药耐药性。
Biomaterials. 2011 Oct;32(30):7711-20. doi: 10.1016/j.biomaterials.2011.06.066. Epub 2011 Aug 4.

引用本文的文献

1
Current Trends and Advances in Nanoplatforms-Based Imaging for Cancer Diagnosis.基于纳米平台的癌症诊断成像的当前趋势与进展
Indian J Microbiol. 2025 Mar;65(1):137-176. doi: 10.1007/s12088-024-01373-9. Epub 2024 Aug 9.
2
Tackling breast cancer with gold nanoparticles: twinning synthesis and particle engineering with efficacy.用金纳米颗粒攻克乳腺癌：孪晶合成与具有疗效的颗粒工程
Nanoscale Adv. 2024 Apr 17;6(11):2766-2812. doi: 10.1039/d3na00988b. eCollection 2024 May 29.
3
Nanomaterial-based CT contrast agents and their applications in image-guided therapy.
基于纳米材料的 CT 对比剂及其在影像引导治疗中的应用。
Theranostics. 2023 Jan 1;13(2):483-509. doi: 10.7150/thno.79625. eCollection 2023.
4
Stimuli-Responsive Gold Nanocages for Cancer Diagnosis and Treatment.用于癌症诊断与治疗的刺激响应型金纳米笼
Pharmaceutics. 2022 Jun 22;14(7):1321. doi: 10.3390/pharmaceutics14071321.
5
pH-Sensitive and Long-Circulation Nanoparticles for Near-Infrared Fluorescence Imaging-Monitored and Chemo-Photothermal Synergistic Treatment Against Gastric Cancer.用于近红外荧光成像监测及光热协同治疗胃癌的pH敏感型长循环纳米粒子
Front Pharmacol. 2020 Nov 26;11:610883. doi: 10.3389/fphar.2020.610883. eCollection 2020.
6
Multifunctional Nanotheranostic Gold Nanocage/Selenium Core-Shell for PAI-Guided Chemo-Photothermal Synergistic Therapy in vivo.多功能纳米诊疗金纳米笼/硒核壳用于体内 PAI 引导的化疗-光热协同治疗。
Int J Nanomedicine. 2020 Dec 17;15:10271-10284. doi: 10.2147/IJN.S275846. eCollection 2020.
7
Recent Advances in Nanomaterials-Based Chemo-Photothermal Combination Therapy for Improving Cancer Treatment.基于纳米材料的化学-光热联合疗法在改善癌症治疗方面的最新进展
Front Bioeng Biotechnol. 2019 Oct 22;7:293. doi: 10.3389/fbioe.2019.00293. eCollection 2019.
8
Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity.具有长效药物作用和降低肝毒性的靶向乙酰胆碱酯酶响应性药物载体。
Int J Nanomedicine. 2019 Jul 26;14:5817-5829. doi: 10.2147/IJN.S215404. eCollection 2019.
9
Current trends and challenges in cancer management and therapy using designer nanomaterials.使用定制纳米材料进行癌症管理与治疗的当前趋势及挑战
Nano Converg. 2019 Jul 15;6(1):23. doi: 10.1186/s40580-019-0193-2.
10
A Biomimetic Gold Nanocages-Based Nanoplatform for Efficient Tumor Ablation and Reduced Inflammation.一种基于仿生金纳米笼的纳米平台，用于高效肿瘤消融和减轻炎症。
Theranostics. 2018 Oct 24;8(19):5362-5378. doi: 10.7150/thno.27631. eCollection 2018.