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用于癌症诊断与治疗的刺激响应型金纳米笼

Stimuli-Responsive Gold Nanocages for Cancer Diagnosis and Treatment.

作者信息

Li Chunming, Zhao Tengyue, Li Lixian, Hu Xiaogang, Li Chao, Chen Wanyi, Hu Yurong

机构信息

Department of Pharmacy, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Chongqing 400030, China.

School of Pharmaceutical Sciences, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou 450001, China.

出版信息

Pharmaceutics. 2022 Jun 22;14(7):1321. doi: 10.3390/pharmaceutics14071321.

DOI:10.3390/pharmaceutics14071321
PMID:35890217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9318695/
Abstract

With advances in nanotechnology, various new drug delivery systems (DDSs) have emerged and played a key role in the diagnosis and treatment of cancers. Over the last two decades, gold nanocages (AuNCs) have been attracting considerable attention because of their outstanding properties. This review summarizes current advancements in endogenous, exogenous, and dual/multi-stimuli responsive AuNCs in drug delivery. This review focuses on the properties, clinical translation potential, and limitations of stimuli-responsive AuNCs for cancer diagnosis and treatment.

摘要

随着纳米技术的进步，各种新型药物递送系统（DDSs）应运而生，并在癌症的诊断和治疗中发挥了关键作用。在过去的二十年里，金纳米笼（AuNCs）因其卓越的性能而备受关注。本文综述了内源性、外源性以及双/多刺激响应性金纳米笼在药物递送方面的当前进展。本文重点关注刺激响应性金纳米笼在癌症诊断和治疗中的性能、临床转化潜力及局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/669f7f365f25/pharmaceutics-14-01321-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/d0317c4b27e7/pharmaceutics-14-01321-sch001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/0f6b77a943c3/pharmaceutics-14-01321-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/e73a08cfedb4/pharmaceutics-14-01321-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/b2165348a1b0/pharmaceutics-14-01321-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/0239b87e6356/pharmaceutics-14-01321-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/e951664fa5a7/pharmaceutics-14-01321-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/669f7f365f25/pharmaceutics-14-01321-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/d0317c4b27e7/pharmaceutics-14-01321-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/8532cc788863/pharmaceutics-14-01321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/312fcbf84445/pharmaceutics-14-01321-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/d0db29746e18/pharmaceutics-14-01321-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/2f66238657bf/pharmaceutics-14-01321-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/cc5182af13a2/pharmaceutics-14-01321-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/1ed783308caa/pharmaceutics-14-01321-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/f5419f81144c/pharmaceutics-14-01321-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/f826a3548494/pharmaceutics-14-01321-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/0f6b77a943c3/pharmaceutics-14-01321-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/e73a08cfedb4/pharmaceutics-14-01321-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/b2165348a1b0/pharmaceutics-14-01321-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/0239b87e6356/pharmaceutics-14-01321-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/e951664fa5a7/pharmaceutics-14-01321-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/9318695/669f7f365f25/pharmaceutics-14-01321-g014.jpg

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