急性心肌梗死患者发生老年环的危险因素。
Risk factors for senile corneal arcus in patients with acute myocardial infarction.
作者信息
Moosavi Mirnaghi, Sareshtedar Ahmad, Zarei-Ghanavati Siamak, Zarei-Ghanavati Mehran, Ramezanfar Nazanin
机构信息
Eye Research Center, Mashhad University of Medical Sciences, Khatam-al-Anbia Eye Hospital, Mashhad, Iran.
出版信息
J Ophthalmic Vis Res. 2010 Oct;5(4):228-31.
PURPOSE
To investigate the association between senile corneal arcus and atherosclerosis risk factors in patients with recent acute myocardial infarction.
METHODS
In this cross sectional study, atherosclerosis risk factors including fasting blood sugar, total cholesterol and triglyceride levels were measured in 165 patients with recent (less than three months' duration) acute myocardial infarction. Slitlamp examination was performed to detect corneal arcus. Associations between senile corneal arcus and atherosclerosis risk factors were assessed.
RESULTS
Overall, 165 patients including 100 male and 65 female subjects with mean age of 62±10.3 years were evaluated. In 122 patients (74%), variable degrees of corneal arcus were observed. The presence of corneal arcus was significantly associated with age (P = 0.03) and high levels of total cholesterol (over 200 mg/dl, P < 0.01). After adjusting for age, arcus was not associated with sex (P = 0.10), hypertriglyceridemia (P = 0.09), fasting blood sugar (P = 0.06), or systemic hypertension (P = 0.08).
CONCLUSION
Our study revealed that corneal arcus is associated with age and hypercholesterolemia in patients with recent acute myocardial infarction. No association was detected with sex, fasting blood sugar, hypertension, and hypertriglyceridemia.
目的
探讨近期急性心肌梗死患者中老年人角膜弓与动脉粥样硬化危险因素之间的关联。
方法
在这项横断面研究中，对165例近期（病程少于三个月）急性心肌梗死患者测量了动脉粥样硬化危险因素，包括空腹血糖、总胆固醇和甘油三酯水平。进行裂隙灯检查以检测角膜弓。评估老年人角膜弓与动脉粥样硬化危险因素之间的关联。
结果
总体上，评估了165例患者，包括100例男性和65例女性，平均年龄为62±10.3岁。在122例患者（74%）中观察到不同程度的角膜弓。角膜弓的存在与年龄（P = 0.03）和总胆固醇水平升高（超过200 mg/dl，P < 0.01）显著相关。在调整年龄后，角膜弓与性别（P = 0.10）、高甘油三酯血症（P = 0.09）、空腹血糖（P = 0.06）或系统性高血压（P = 0.08）无关。
结论
我们的研究表明，近期急性心肌梗死患者的角膜弓与年龄和高胆固醇血症相关。未发现与性别、空腹血糖、高血压和高甘油三酯血症有关联。
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