光感受器间类视黄醇结合蛋白：谜团与奥秘 - Suppr

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超能文献

Interphotoreceptor retinoid binding protein; myths and mysteries.

作者信息

Gonzalez-Fernandez Federico

机构信息

Medical Research Service, Veterans Affairs Medical Center, Buffalo, New York, USA.

出版信息

J Ophthalmic Vis Res. 2012 Jan;7(1):100-4.

PMID:22737397

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3381098/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c4d/3381098/d8d0dabc1c30/jovr-07-100f1.jpg

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Interphotoreceptor retinoid binding protein; myths and mysteries.光感受器间类视黄醇结合蛋白：谜团与奥秘

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Albumin is not present in the murine interphotoreceptor matrix, or in that of transgenic mice lacking IRBP.白蛋白不存在于小鼠的光感受器间基质中，也不存在于缺乏IRBP的转基因小鼠的光感受器间基质中。

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Retinoid specificity of interphotoreceptor retinoid-binding protein.视网膜色素上皮细胞间类视黄醇结合蛋白的类视黄醇特异性

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本文引用的文献

Cone outer segment extracellular matrix as binding domain for interphotoreceptor retinoid-binding protein.视锥外节细胞外基质作为光感受器间视网膜结合蛋白的结合域。

J Comp Neurol. 2012 Mar 1;520(4):756-69. doi: 10.1002/cne.22773.

Exaggerated eye growth in IRBP-deficient mice in early development.早期发育中缺乏 IRBP 的小鼠眼睛过度生长。

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5804-11. doi: 10.1167/iovs.10-7129.

Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle.视锥细胞光循环中 11-顺式视黄醇的生理相关载体为光感受器间维生素 A 结合蛋白。

J Neurosci. 2011 Mar 23;31(12):4714-9. doi: 10.1523/JNEUROSCI.3722-10.2011.

Interphotoreceptor retinoid-binding protein (IRBP) is downregulated at early stages of diabetic retinopathy.糖尿病性视网膜病变早期，光感受器间维生素 A 结合蛋白（IRBP）下调。

Diabetologia. 2009 Dec;52(12):2633-41. doi: 10.1007/s00125-009-1548-8. Epub 2009 Oct 13.

Retinol-binding site in interphotoreceptor retinoid-binding protein (IRBP): a novel hydrophobic cavity.光感受器间类视黄醇结合蛋白（IRBP）中的视黄醇结合位点：一个新的疏水腔。

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5577-86. doi: 10.1167/iovs.08-1857. Epub 2009 Jul 15.

The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors.光感受器间类视黄醇结合蛋白在视觉类视黄醇转运及视锥光感受器功能中的作用。

J Neurosci. 2009 Feb 4;29(5):1486-95. doi: 10.1523/JNEUROSCI.3882-08.2009.

A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa.IRBP基因（RBP3）中的纯合错义突变与常染色体隐性视网膜色素变性相关。

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1864-72. doi: 10.1167/iovs.08-2497. Epub 2008 Dec 13.

Module structure of interphotoreceptor retinoid-binding protein (IRBP) may provide bases for its complex role in the visual cycle - structure/function study of Xenopus IRBP.光感受器间类视黄醇结合蛋白（IRBP）的模块结构可能为其在视觉循环中的复杂作用提供基础——非洲爪蟾IRBP的结构/功能研究

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Interphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments.光感受器间类视黄醇结合蛋白是从视杆光感受器外段移除视黄醇的生理相关载体。

Biochemistry. 2007 Jul 24;46(29):8669-79. doi: 10.1021/bi7004619. Epub 2007 Jun 30.

Focus on Molecules: interphotoreceptor retinoid-binding protein (IRBP).

Exp Eye Res. 2008 Feb;86(2):169-70. doi: 10.1016/j.exer.2006.09.003. Epub 2007 Jan 12.

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