Fani M M, Ebrahimi H, Pourshahidi S, Aflaki E, Shafiee Sarvestani S
Department of Oral Medicine, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran Red Crescent Med J. 2012 Feb;14(2):75-8. Epub 2012 Feb 1.
Recurrent aphthous stomatitis (RAS) appears to be the most common type of oral ulcers. The lesion is usually self limited but its painful presentation results in some difficulties. Therefore, an efficient therapeutic strategy is required and currently existing therapies seem to be inadequate because of its unclear etiology. Here the therapeutic effect of triamcinolone acetonide ointment as a relatively expensive medication has been compared with phenytoin syrup on aphthous ulcers in patients with Behcet's syndrome.
Thirty out of 60 our patients with Behcet's syndrome were randomly treated by phenytoin syrup and the remaining were advised to use 0.1% triamcinolone acetonide ointment. After a week, they were visited again to determine the status of aphthous ulcers.
Positive response in the triamcinolone acetonide group and phenytoin group was 86.7% and 53.3%, respectively.
The effectiveness of triamcinolone acetonide ointment was more than phenytoin on aphthous ulcers in patients with Behcet's syndrome.
复发性阿弗他口炎（RAS）似乎是最常见的口腔溃疡类型。该病变通常为自限性，但其疼痛表现会带来一些困扰。因此，需要一种有效的治疗策略，而由于其病因不明，目前现有的治疗方法似乎并不充分。在此，将相对昂贵的药物曲安奈德软膏与苯妥英糖浆对贝赫切特综合征患者口腔溃疡的治疗效果进行了比较。
我们的60例贝赫切特综合征患者中，30例随机接受苯妥英糖浆治疗，其余患者则被建议使用0.1%曲安奈德软膏。一周后，再次对他们进行访视以确定阿弗他溃疡的状况。
曲安奈德组和苯妥英组的阳性反应分别为86.7%和53.3%。
曲安奈德软膏对贝赫切特综合征患者口腔溃疡的疗效优于苯妥英。
