地塞米松软膏联合曲安奈德治疗复发性阿弗他口炎的对比研究
A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis.
作者信息
Kumar Vivek, Singh Chintu Kumar, Arvind Ananya, Ahsan Aasia, Kumar Sudhanshu, Das Debeswar, Kumari Subham
机构信息
Department of Oral Medicine and Radiology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, India.
Department of Oral and Maxillofacial Surgery, B.R. Ambedkar Institute of Dental Science and Hospital, Patna, Bihar, India.
出版信息
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1325-S1328. doi: 10.4103/jpbs.jpbs_102_23. Epub 2023 Apr 28.
AIM
To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS).
MATERIALS AND METHODS
This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups-the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers.
RESULTS
The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS.
CONCLUSION
Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments.
目的
评估并比较地塞米松软膏与曲安奈德凝胶剂型治疗轻度复发性阿弗他口炎（RAS）的疗效。
材料与方法
这是一项针对60例临床诊断为RAS的患者的随机临床试验，这些患者被随机分为两组——地塞米松软膏组（第一组）和曲安奈德凝胶组（第二组）。要求患者每天在每个溃疡上涂抹三次凝胶。根据溃疡疼痛、大小和数量消退所需的时间来评估凝胶的疗效。
结果
结果显示，7天内第一组和第二组在溃疡大小、疼痛、数量和持续时间方面存在显著差异。然而，在两组中，治疗RAS时均未观察到显著差异。
结论
经临床评估，地塞米松软膏在该治疗中有效且安全。
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