Robbertse B, Tatusova T
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, 45 Center Drive, Bethesda, MD 20892.
Mycology. 2011 Sep;2(3):142-160. doi: 10.1080/21501203.2011.584576.
The National Center for Biotechnology Information (NCBI) is well known for the nucleotide sequence archive, GenBank and sequence analysis tool BLAST. However, NCBI integrates many types of biomolecular data from variety of sources and makes it available to the scientific community as interactive web resources as well as organized releases of bulk data. These tools are available to explore and compare fungal genomes. Searching all databases with Fungi [organism] at http://www.ncbi.nlm.nih.gov/ is the quickest way to find resources of interest with fungal entries. Some tools though are resources specific and can be indirectly accessed from a particular database in the Entrez system. These include graphical viewers and comparative analysis tools such as TaxPlot, TaxMap and UniGene DDD (found via UniGene Homepage). Gene and BioProject pages also serve as portals to external data such as community annotation websites, BioGrid and UniProt. There are many different ways of accessing genomic data at NCBI. Depending on the focus and goal of research projects or the level of interest, a user would select a particular route for accessing genomic databases and resources. This review article describes methods of accessing fungal genome data and provides examples that illustrate the use of analysis tools.
美国国立生物技术信息中心（NCBI）以核苷酸序列存档库GenBank和序列分析工具BLAST而闻名。然而，NCBI整合了来自各种来源的多种生物分子数据，并以交互式网络资源以及批量数据的有组织发布的形式向科学界提供这些数据。这些工具可用于探索和比较真菌基因组。在http://www.ncbi.nlm.nih.gov/上使用“真菌 [生物体]”搜索所有数据库是找到包含真菌条目的感兴趣资源的最快方法。不过，有些工具是特定资源的，可以从Entrez系统中的特定数据库间接访问。这些工具包括图形查看器和比较分析工具，如TaxPlot、TaxMap和UniGene DDD（可通过UniGene主页找到）。基因和生物项目页面也充当通向外部数据的门户，如社区注释网站、BioGrid和UniProt。在NCBI有许多不同的访问基因组数据的方式。根据研究项目的重点和目标或兴趣程度，用户会选择特定的途径来访问基因组数据库和资源。这篇综述文章描述了访问真菌基因组数据的方法，并提供了说明分析工具使用的示例。
