美国国立生物技术信息中心的数据库资源。

Database resources of the National Center for Biotechnology Information.

作者信息

Wheeler D L, Chappey C, Lash A E, Leipe D D, Madden T L, Schuler G D, Tatusova T A, Rapp B A

机构信息

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.

出版信息

Nucleic Acids Res. 2000 Jan 1;28(1):10-4. doi: 10.1093/nar/28.1.10.

Abstract

In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval and resources that operate on the data in GenBank and a variety of other biological data made available through NCBI's Web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser. Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing pages, GeneMap'99, Davis Human-Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP) pages, Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, Cancer Genome Anatomy Project (CGAP) pages, SAGEmap, Online Mendelian Inheritance in Man (OMIM) and the Molecular Modeling Database (MMDB). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih. gov

摘要

除维护GenBank®核酸序列数据库外,美国国立生物技术信息中心(NCBI)还提供数据分析与检索服务,以及基于GenBank数据和通过NCBI网站提供的各种其他生物数据运行的资源。NCBI数据检索资源包括Entrez、PubMed、LocusLink和分类浏览器。数据分析资源包括BLAST、电子PCR、开放阅读框查找器、参考序列、单基因簇、单核苷酸多态性数据库(dbSNP)、人类基因组测序页面、基因图谱99、戴维斯人类-小鼠同源性图谱、癌症染色体畸变项目(CCAP)页面、Entrez基因组、直系同源簇(COG)数据库、逆转录病毒基因分型工具、癌症基因组解剖项目(CGAP)页面、SAGEmap、《人类孟德尔遗传在线》(OMIM)和分子建模数据库(MMDB)。许多网络应用程序都增强了BLAST程序的定制实现,这些实现经过优化可搜索特定数据集。所有资源均可通过NCBI主页访问:http://www.ncbi.nlm.nih.gov

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