NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
EPMA J. 2011 Dec 24;3(1):2. doi: 10.1007/s13167-011-0136-4.
Multiple sclerosis (MS) is the most common chronic inflammatory disorder of the central nervous system (CNS) in young adults. The disease causes a wide range of symptoms depending on the localization and characteristics of the CNS pathology. In addition to drug-based immunomodulatory treatment, both drug-based and non-drug approaches are established as complementary strategies to alleviate existing symptoms and to prevent secondary diseases. In particular, physical therapy like exercise and physiotherapy can be customized to the individual patient's needs and has the potential to improve the individual outcome. However, high quality systematic data on physical therapy in MS are rare. This article summarizes the current knowledge on the influence of physical activity and exercise on disease-related symptoms and physical restrictions in MS patients. Other treatment strategies such as drug treatments or cognitive training were deliberately excluded for the purposes of this article.
多发性硬化症（MS）是年轻人中枢神经系统（CNS）最常见的慢性炎症性疾病。该疾病会导致一系列症状，具体取决于 CNS 病理学的定位和特征。除了基于药物的免疫调节治疗外，基于药物和非药物的方法也被确立为缓解现有症状和预防继发性疾病的补充策略。特别是，运动和物理疗法等身体疗法可以根据患者的个体需求进行定制，并有潜力改善个体的治疗效果。然而，关于多发性硬化症身体疗法的高质量系统数据却很少。本文总结了目前关于身体活动和运动对 MS 患者疾病相关症状和身体限制影响的知识。出于本文的目的，其他治疗策略，如药物治疗或认知训练，被故意排除在外。
