Madrid-Costa David, Isla-Paradelo Leticia, García-Lázaro Santiago, Albarrán-Diego César, Ruiz-Alcocer Javier
Optometry Research Group, Optics Department, University of Valencia, Spain.
Clin Exp Optom. 2013 Jan;96(1):53-7. doi: 10.1111/j.1444-0938.2012.00758.x. Epub 2012 Jun 28.
Simultaneous vision multifocal contact lenses are widely used to alleviate the symptoms of presbyopia. These contact lenses create simultaneous retinal images due to the incoming light distribution being divided into two or more focuses. Our aim was to evaluate whether the multizone refractive multifocal contact lenses affect the measurements of the retinal nerve fibre layer (RNFL) and macular thickness using optical coherence tomography (OCT).
In this cross-over study, 30 eyes of 30 subjects with a mean age of 50.42 ± 7.82 years were fitted with multizone refractive multifocal contact lenses. Using the RNFL Thickness Analysis mode of the Cirrus HD (Carl Zeiss, Meditec, Dublin, CA, USA) OCT, the average, superior, nasal, inferior, temporal and 12 o'clock-hour retinal nerve fibre layer thicknesses were obtained. In Macular Thickness Analysis mode of Cirrus HD OCT, the average cube thickness, macular cube volume, central subfield thickness, inner and outer macular thickness (superior, inferior, nasal and temporal area) were obtained. Measurements were performed with and without contact lenses.
Statistically significant differences were not found in RNFL thickness at any of the studied areas and for 12 o'clock-hour sectors analysed (p > 0.07). The mean macular volume was 9.86 ± 0.30 mm(3) and 9.87 ± 0.27 mm(3) with and without multifocal contact lenses, respectively (p = 0.38). There were no statistically significant differences in average macular thickness or macular thickness of areas analysed between the measurements with and without multifocal contact lenses (p > 0.09). The signal strength was higher than seven for all scans, and differences were not found in the mean of signal strength between the measurements with and without contact lenses.
The results of this study suggest that the assessed multizone refractive multifocal contact lens does not affect the retinal nerve fibre layer and macular thickness measurements using Cirrus HD OCT.
同步视觉多焦点隐形眼镜被广泛用于缓解老花眼症状。由于入射光分布被分为两个或更多焦点,这些隐形眼镜会产生同步视网膜图像。我们的目的是评估多区域折射多焦点隐形眼镜是否会影响使用光学相干断层扫描(OCT)测量视网膜神经纤维层(RNFL)和黄斑厚度。
在这项交叉研究中,为30名平均年龄为50.42±7.82岁的受试者的30只眼睛佩戴了多区域折射多焦点隐形眼镜。使用Cirrus HD(卡尔蔡司,医疗技术公司,美国加利福尼亚州都柏林)OCT的RNFL厚度分析模式,获得平均、上方、鼻侧、下方、颞侧和12点处的视网膜神经纤维层厚度。在Cirrus HD OCT的黄斑厚度分析模式下,获得平均立方体厚度、黄斑立方体体积、中心子区域厚度、黄斑内外厚度(上方、下方、鼻侧和颞侧区域)。在佩戴和不佩戴隐形眼镜的情况下进行测量。
在任何研究区域以及分析的12点扇形区域的RNFL厚度中均未发现统计学上的显著差异(p>0.07)。佩戴和不佩戴多焦点隐形眼镜时,平均黄斑体积分别为9.86±0.30 mm³和9.87±0.27 mm³(p = 0.38)。在佩戴和不佩戴多焦点隐形眼镜的测量之间,分析区域的平均黄斑厚度或黄斑厚度没有统计学上的显著差异(p>0.09)。所有扫描的信号强度均高于7,并且在佩戴和不佩戴隐形眼镜的测量之间,信号强度的平均值没有差异。
本研究结果表明,所评估的多区域折射多焦点隐形眼镜不会影响使用Cirrus HD OCT测量视网膜神经纤维层和黄斑厚度。