Abedon S T
Department of Microbiology and Immunology, University of Arizona, Tucson 85724.
J Theor Biol. 1990 Oct 21;146(4):501-11. doi: 10.1016/s0022-5193(05)80375-3.
For Escherichia coli cells that have been infected by T-even bacteriophages (phages T2, T4, and T6), the adsorption of a second T-even phage results in an increase in the length of the original phage infection and an associated increase in the number of phages produced by the same infected cell. This is a phage encoded response called lysis inhibition. In this study the ecological significance of lysis inhibition is explored. In particular it is argued that lysis inhibition is an adaptive response to environments containing high concentrations of infected cells and low concentrations of uninfected cells.
对于已被T偶数噬菌体(噬菌体T2、T4和T6)感染的大肠杆菌细胞,第二个T偶数噬菌体的吸附会导致原始噬菌体感染时间延长,且同一被感染细胞产生的噬菌体数量相应增加。这是一种由噬菌体编码的反应,称为裂解抑制。在本研究中,探讨了裂解抑制的生态学意义。特别是有人认为,裂解抑制是对含有高浓度感染细胞和低浓度未感染细胞的环境的一种适应性反应。