Department of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Med Sci Monit. 2012 Jul;18(7):MT60-5. doi: 10.12659/msm.883199.
The use of contrast media and the time-resolved imaging of contrast kinetics (TRICKS) technique have some theoretical advantages over time-of-flight magnetic resonance angiography (TOF-MRA) in the follow-up of intracranial aneurysms after endovascular treatment. We prospectively compared the diagnostic performance of TRICKS and TOF-MRA with digital subtracted angiography (DSA) in the assessment of occlusion of embolized aneurysms.
MATERIAL/METHODS: Seventy-two consecutive patients with 72 aneurysms were examined 3 months after embolization. Test characteristics of TOF-MRA and TRICKS were calculated for the detection of residual flow. The results of quantification of flow were compared with weighted kappa. Intraobserver and interobserver reproducibility was determined.
The sensitivity of TOF-MRA was 85% (95% CI, 65-96%) and of TRICKS, 89% (95% CI, 70-97%). The specificity of both methods was 91% (95% CI, 79-98%). The accuracy of the flow quantification ranged from 0.76 (TOF-MRA) to 0.83 (TRICKS). There was no significant difference between the methods in the area under the ROC curve regarding both the detection and the quantification of flow. Intraobserver reproducibility was very good with both techniques (kappa, 0.86-0.89). The interobserver reproducibility was moderate for TOF-MRA and very good for TRICKS (kappa, 0.74-0.80).
In this study, TOF-MRA and TRICKS presented similar diagnostic performance; therefore, the use of time-resolved contrast-enhanced MRA is not justified in the follow-up of embolized aneurysms.
与时间飞越磁共振血管造影术（TOF-MRA）相比，使用对比剂和对比剂动力学的时间分辨成像（TRICKS）技术在颅内动脉瘤血管内治疗后的随访中有一些理论优势。我们前瞻性地比较了 TRICKS 和 TOF-MRA 与数字减影血管造影（DSA）在评估栓塞动脉瘤闭塞中的诊断性能。
材料/方法：72 例 72 个动脉瘤患者在栓塞后 3 个月进行检查。计算了 TOF-MRA 和 TRICKS 的检测残余血流的测试特征。定量分析血流的结果与加权kappa 进行比较。确定了观察者内和观察者间的可重复性。
TOF-MRA 的灵敏度为 85%（95%CI，65-96%），TRICKS 的灵敏度为 89%（95%CI，70-97%）。两种方法的特异性均为 91%（95%CI，79-98%）。流量量化的准确性范围为 0.76（TOF-MRA）至 0.83（TRICKS）。在检测和量化流量方面，两种方法的 ROC 曲线下面积均无显著差异。两种技术的观察者内可重复性均非常好（kappa，0.86-0.89）。TOF-MRA 的观察者间可重复性为中度，而 TRICKS 的观察者间可重复性非常好（kappa，0.74-0.80）。
在这项研究中，TOF-MRA 和 TRICKS 表现出相似的诊断性能；因此，在栓塞动脉瘤的随访中，使用时间分辨对比增强 MRA 是没有道理的。
