Sun Chengtao, Sheng Wei, Yu Huiming, Han Junqing
Tumor Research and Therapy Center, Provincial Hospital affiliated to Shandong University, Shandong University, Jinan, Shandong 250021, P.R. China.
Oncol Lett. 2012 Mar;3(3):718-720. doi: 10.3892/ol.2012.555. Epub 2012 Jan 4.
Localized forms of giant cell tumors are defined as giant cell tumors of the tendon sheath (GCTTS). GCTTS arises from the synovium of a joint, bursa or tendon sheath, and 85% of the tumors occur in the fingers. GCTTS in the knee is extremely rare. We report an unusual case of a 15-year-old boy who presented with an occult growing swelling and a 2-month history of infra-patellar pain in the left knee. Magnetic resonance imaging (MRI) demonstrated a well-circumscribed soft tissue mass in the infra-patellar fat pad posterior to the patella tendon. Excision biopsy was performed by surgical removal. Histopathological examination revealed that it was GCTTS. During the follow-up period, his recovery was propitious and there was no recurrence. Owing to its few and non-specific symptoms, and local recurrence varying from 9 to 44%, its proper, early diagnosis and appropriate treatment is necessary. The purpose for which we report the case is to emphasize the possibility of GCTTS where there is a mass with non-specific symptoms such as infra-patellar pain of the knee, and to avoid misdiagnosis where possible.
局限性巨细胞瘤被定义为腱鞘巨细胞瘤(GCTTS)。GCTTS起源于关节、滑囊或腱鞘的滑膜,85%的肿瘤发生在手指。GCTTS在膝关节极为罕见。我们报告了一例不寻常的病例,一名15岁男孩,表现为隐匿性生长的肿胀和左膝髌下疼痛2个月的病史。磁共振成像(MRI)显示髌腱后方髌下脂肪垫有一个边界清晰的软组织肿块。通过手术切除进行切除活检。组织病理学检查显示为GCTTS。在随访期间,他恢复良好,没有复发。由于其症状较少且不具特异性,局部复发率在9%至44%之间,因此进行恰当的早期诊断和适当的治疗是必要的。我们报告该病例的目的是强调在出现如膝关节髌下疼痛等非特异性症状的肿块时存在GCTTS的可能性,并尽可能避免误诊。