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本文引用的文献

1
Eyelid basal cell carcinoma developing in an epidermoid cyst: a previously unreported event.在表皮样囊肿中发生的眼睑基底细胞癌:一个此前未报道过的事件。
Ophthalmic Plast Reconstr Surg. 2010 Nov-Dec;26(6):491-4. doi: 10.1097/IOP.0b013e3181d92972.
2
Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.眼睑皮肤肿瘤的临床病理特征。5504例回顾性研究及文献复习。
Am J Dermatopathol. 2009 May;31(3):256-62. doi: 10.1097/DAD.0b013e3181961861.
3
Hidrocystomas--a brief review.汗管囊肿瘤——简要综述。
MedGenMed. 2006 Sep 6;8(3):57.
4
Collision sebaceous and basal cell carcinomas of the eyelid.眼睑皮脂腺癌与基底细胞癌的碰撞
Ann Diagn Pathol. 2006 Jun;10(3):157-9. doi: 10.1016/j.anndiagpath.2005.07.018.
5
A case of cutaneous collision tumour: the importance of photographic documentation and large incisional biopsy.一例皮肤碰撞瘤:摄影记录和大切口活检的重要性。
Eye (Lond). 2006 Nov;20(11):1324-5. doi: 10.1038/sj.eye.6702192. Epub 2006 Mar 31.
6
Basal cell-signet-ring squamous cell carcinoma of the eyelid.眼睑基底细胞-印戒样鳞状细胞癌
Arch Pathol Lab Med. 2006 Mar;130(3):393-6. doi: 10.5858/2006-130-393-BCSCCO.
7
Treatment of multiple apocrine hidrocystomas with trichloroacetic acid.用三氯乙酸治疗多发性顶泌汗腺囊瘤。
Ophthalmic Plast Reconstr Surg. 2005 Mar;21(2):148-50. doi: 10.1097/01.iop.0000155509.54813.93.
8
Cystic basal cell carcinoma or hidrocytoma? The use of an excisional biopsy in a histopathologically challenging case.囊性基底细胞癌还是汗腺囊瘤?在一例组织病理学诊断困难的病例中采用切除活检术
Am J Dermatopathol. 2004 Feb;26(1):67-9. doi: 10.1097/00000372-200402000-00010.
9
Non-Hodgkin lymphoma and Kaposi sarcoma in an eyelid of a patient with acquired immunodeficiency syndrome. Multiple viruses in pathogenesis.获得性免疫缺陷综合征患者眼睑的非霍奇金淋巴瘤和卡波西肉瘤。发病机制中的多种病毒。
Arch Ophthalmol. 1997 Nov;115(11):1464-6. doi: 10.1001/archopht.1997.01100160634020.
10
Cutaneous collision tumors. An analysis of 69 cases and review of the literature.皮肤碰撞瘤:69例分析及文献复习
Am J Dermatopathol. 1994 Jun;16(3):253-7.

良性还是恶性眼睑肿块——你能分辨出来吗?一例罕见的碰撞瘤凸显了鉴别汗腺囊瘤和基底细胞癌的困难。

A benign or malignant eyelid lump--can you tell? An unusual collision tumour highlighting the difficulty differentiating a hidrocystoma from a basal cell carcinoma.

作者信息

Jayaprakasam Anuradha, Rene Cornelius

机构信息

Ophthalmology Department, Addenbrooke's hospital, Cambridge, UK.

出版信息

BMJ Case Rep. 2012 Jun 28;2012:bcr1220115307. doi: 10.1136/bcr.12.2011.5307.

DOI:10.1136/bcr.12.2011.5307
PMID:22744259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3448349/
Abstract

Hidrocystoma and basal cell carcinoma (BCC) are common eyelid lesions. The former is benign while the latter is malignant and can cause significant destruction of the adnexal structures, orbital invasion and visual loss. The authors describe a case of a 76-year-old female with a slow growing right upper lid lesion which was diagnosed as a hidrocystoma but excision biopsy revealed a collision tumour comprised of a BCC abutting a hidrocystoma in the same lesion. Cystic BCC can masquerade as hidrocystoma but there are no previous case reports of BCC coexisting with hidrocystoma in the same lesion. This case highlights the fact that apparently benign lesions, such as hidrocystomas, may actually be malignant or coexist with malignant pathology. Clinicians should have a low threshold for appropriate excision biopsy and histological examination of such lesions, especially if there are sinister features, such as lash loss, induration, pigmentation or a pearly appearance.

摘要

汗管瘤和基底细胞癌(BCC)是常见的眼睑病变。前者是良性的,而后者是恶性的,可导致附属器结构的严重破坏、眼眶侵犯和视力丧失。作者描述了一例76岁女性,其右上睑有一生长缓慢的病变,最初诊断为汗管瘤,但切除活检显示为碰撞瘤,同一病变中基底细胞癌与汗管瘤相邻。囊性基底细胞癌可伪装成汗管瘤,但此前尚无同一病变中基底细胞癌与汗管瘤共存的病例报告。该病例凸显了这样一个事实,即看似良性的病变,如汗管瘤,实际上可能是恶性的,或与恶性病理共存。临床医生对此类病变进行适当的切除活检和组织学检查的阈值应较低,尤其是当存在睫毛脱落、硬结、色素沉着或珍珠样外观等不祥特征时。