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良性还是恶性眼睑肿块——你能分辨出来吗?一例罕见的碰撞瘤凸显了鉴别汗腺囊瘤和基底细胞癌的困难。

A benign or malignant eyelid lump--can you tell? An unusual collision tumour highlighting the difficulty differentiating a hidrocystoma from a basal cell carcinoma.

作者信息

Jayaprakasam Anuradha, Rene Cornelius

机构信息

Ophthalmology Department, Addenbrooke's hospital, Cambridge, UK.

出版信息

BMJ Case Rep. 2012 Jun 28;2012:bcr1220115307. doi: 10.1136/bcr.12.2011.5307.

Abstract

Hidrocystoma and basal cell carcinoma (BCC) are common eyelid lesions. The former is benign while the latter is malignant and can cause significant destruction of the adnexal structures, orbital invasion and visual loss. The authors describe a case of a 76-year-old female with a slow growing right upper lid lesion which was diagnosed as a hidrocystoma but excision biopsy revealed a collision tumour comprised of a BCC abutting a hidrocystoma in the same lesion. Cystic BCC can masquerade as hidrocystoma but there are no previous case reports of BCC coexisting with hidrocystoma in the same lesion. This case highlights the fact that apparently benign lesions, such as hidrocystomas, may actually be malignant or coexist with malignant pathology. Clinicians should have a low threshold for appropriate excision biopsy and histological examination of such lesions, especially if there are sinister features, such as lash loss, induration, pigmentation or a pearly appearance.

摘要

汗管瘤和基底细胞癌(BCC)是常见的眼睑病变。前者是良性的,而后者是恶性的,可导致附属器结构的严重破坏、眼眶侵犯和视力丧失。作者描述了一例76岁女性,其右上睑有一生长缓慢的病变,最初诊断为汗管瘤,但切除活检显示为碰撞瘤,同一病变中基底细胞癌与汗管瘤相邻。囊性基底细胞癌可伪装成汗管瘤,但此前尚无同一病变中基底细胞癌与汗管瘤共存的病例报告。该病例凸显了这样一个事实,即看似良性的病变,如汗管瘤,实际上可能是恶性的,或与恶性病理共存。临床医生对此类病变进行适当的切除活检和组织学检查的阈值应较低,尤其是当存在睫毛脱落、硬结、色素沉着或珍珠样外观等不祥特征时。

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