Lee Eun Jung, Park Yong Won, Hong Young Mi, Lee Joon Sung, Han Ji Whan
Department of Pediatrics, The Catholic University of Korea School of Medicine, Seoul, Korea.
Korean J Pediatr. 2012 Jun;55(6):202-5. doi: 10.3345/kjp.2012.55.6.202. Epub 2012 Jun 21.
This study investigated the epidemiology of Kawasaki disease (KD) in infants ≤3-month-old.
To study the epidemiology of KD in Korea, data for 27,851 KD patients were collected on a 3-year basis between 2000 and 2008 in a retrospective survey. From this, data for 609 KD patients ≤3-month-old were analyzed and compared with the data for KD patients >3-month-old.
The 609 KD patients ≤3-month-old (385 males and 224 females) constituted 2.2% of the KD patients. They included 25 infants <1-month-old, 198 infants ≤1- to 2-month-old, and 386 infants >2- and 3-months-old. The ratio of males to females was 1.72:1. The incidence of coronary artery (CA) dilatation (19.9% vs. 18.7%) and CA aneurysms (3.4% vs. 2.6%) detected by echocardiography did not differ significantly between patients with KD younger and older than 3-month-old.
Compared with the data for the KD patients >3-month-old, the data for the 609 patients ≤3-month-old did not show a significantly higher incidence of CA dilatation or CA aneurysms.
本研究调查了3个月及以下婴儿川崎病（KD）的流行病学情况。
为研究韩国KD的流行病学，在一项回顾性调查中，于2000年至2008年的3年时间里收集了27851例KD患者的数据。从中分析了609例3个月及以下KD患者的数据，并与3个月以上KD患者的数据进行比较。
609例3个月及以下KD患者（385例男性和224例女性）占KD患者的2.2%。其中包括25例1个月以下婴儿、198例1至2个月婴儿和386例2至3个月婴儿。男女比例为1.72:1。通过超声心动图检测到的冠状动脉（CA）扩张发生率（19.9%对18.7%）和CA动脉瘤发生率（3.4%对2.6%）在3个月以下和3个月以上KD患者之间无显著差异。
与3个月以上KD患者的数据相比，609例3个月及以下患者的CA扩张或CA动脉瘤发生率未显著升高。
