Park Yong Won, Han Ji Whan, Park In Sook, Kim Chang Hwi, Yun Yong Soo, Cha Sung Ho, Ma Jae Sook, Lee Sang Bum, Kim Chul Ho, Lee Heung Jae, Tockgo Young Chang
Department of Pediatrics, Inje University, Seoul, Korea.
Pediatr Int. 2005 Aug;47(4):382-7. doi: 10.1111/j.1442-200x.2005.02079.x.
The aim of this study was to investigate the incidence rate and epidemiologic patterns of Kawasaki disease in Korea for a 3 year period during 2000 to 2002.
An epidemiologic survey on Kawasaki disease was retrospectively performed. The questionnaire was sent to all 112 hospitals having pediatric residency programs, and obtained data were analyzed.
The 9150 cases of Kawasaki disease from 92 hospitals which responded (response rate, 82.1%) included 5515 males and 3635 females (male : female ratio, 1.52:1). The incidence rate per 100,000 children <5 years old was 73.7 in 2000, and increased to 90.8 in 2001, and 95.5 in 2002 (average rate, 86.4). The monthly number of patients was slightly higher in May, June and July. Their mean age of onset, the proportion of sibling cases, and a rate of recurrent cases were 30.5 months, 0.17%, and 2.9%, respectively. Coronary arterial abnormalities occurred in 18.6% of cases including dilatations of 17.3% and aneurysms of 3.1%.
The average annual incidence, 86.4/100 000 in children <5 years old is the second highest rate in the world.
本研究旨在调查2000年至2002年期间韩国3年里川崎病的发病率及流行病学模式。
对川崎病进行回顾性流行病学调查。向所有112家设有儿科住院医师培训项目的医院发放问卷，并对收集到的数据进行分析。
92家做出回应的医院（回应率为82.1%）上报了9150例川崎病病例，其中男性5515例，女性3635例（男∶女比例为1.52∶1）。2000年每10万名5岁以下儿童中的发病率为73.7，2001年增至90.8，2002年为95.5（平均发病率为86.4）。5月、6月和7月的月病例数略高。发病的平均年龄、同胞患病比例及复发率分别为30.5个月、0.17%和2.9%。18.6%的病例出现冠状动脉异常，其中17.3%为冠状动脉扩张，3.1%为冠状动脉瘤。
5岁以下儿童的年平均发病率为86.4/10万，是世界第二高发病率。
