韩国城市儿童血清γ-谷氨酰转移酶水平与超重之间的关系
The Relationship between Serum Gamma-glutamyltransferase Level and Overweight in Korean Urban Children.
作者信息
Cho Young-Gyu, Park Kyung-Hee, Kim Chan-Won, Hur Yang-Im
机构信息
Department of Family Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
出版信息
Korean J Fam Med. 2011 Mar;32(3):182-8. doi: 10.4082/kjfm.2011.32.3.182. Epub 2011 Mar 31.
BACKGROUND
Recently, it has been reported that gamma-glumyltransferase (GGT) is associated with various cardiovascular risk factors including overweight in adults. However, there are few studies on the relationship between GGT and cardiovascular risk factors in children. The aim of this study was to assess the relationship between serum GGT level and overweight in Korean urban children.
METHODS
This study was a cross-sectional study using data on 390 4th grade students of elementary schools in Gunpo, Korea. Children were divided into 4 groups according to gender-specific quartiles of serum GGT level. Body mass index, waist circumference and body fat percentage were quantified as adiposity indices.
RESULTS
All adiposity indices in children of the highest GGT level quartile were higher than those in children of the lowest quartile. Adjusted odd ratios on overweight of the highest quartile of GGT level compared to the lowest quartile were 14.40 (95% confidence interval [CI], 4.43 to 46.83) in boys and 2.94 (95% CI, 1.06 to 8.16) in girls.
CONCLUSION
This study shows that high serum GGT level is related with overweight in Korean urban children and this relationship is stronger in boys compared to girls.
背景
最近，有报道称γ-谷氨酰转移酶（GGT）与包括成年人超重在内的多种心血管危险因素相关。然而，关于儿童GGT与心血管危险因素之间关系的研究较少。本研究的目的是评估韩国城市儿童血清GGT水平与超重之间的关系。
方法
本研究是一项横断面研究，使用了韩国军浦市390名小学四年级学生的数据。根据血清GGT水平的性别特异性四分位数将儿童分为4组。将体重指数、腰围和体脂百分比量化为肥胖指标。
结果
GGT水平最高四分位数组儿童的所有肥胖指标均高于最低四分位数组儿童。与最低四分位数相比，GGT水平最高四分位数组超重的校正比值比在男孩中为14.40（95%置信区间[CI]，4.43至46.83），在女孩中为2.94（95%CI，1.06至8.16）。
结论
本研究表明，韩国城市儿童血清GGT水平高与超重有关，且这种关系在男孩中比女孩中更强。
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