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Contact dermatitis in a child from methlychloroisothiazolinone and methylisothiazolinone in moist wipes.

作者信息

Kazandjieva Jana, Gergovska Malena, Darlenski Razvigor

机构信息

Department of Dermatology and Venereology, Medical Faculty, Medical University, Sofia, BulgariaDepartment of Dermatology and Venereology, Tokuda Hospital, Sofia, Bulgaria.

出版信息

Pediatr Dermatol. 2014 Mar-Apr;31(2):225-7. doi: 10.1111/j.1525-1470.2012.01804.x. Epub 2012 Jul 2.

DOI:10.1111/j.1525-1470.2012.01804.x
PMID:22747892
Abstract

Contact allergic reactions to methlychloroisothiazolinone/methylisothiazolinone also widely known as Kathon CG have been reported extensively reported. It is one of the most commonly used preservatives in rinse-off products, cosmetics, and others. Herein, a case of a 50-year-old girl is presented with chronic dermatitis in the anogenital area. The patient was patch tested and had positive reaction to Kathon CG. The detailed history taking revealed that the allergen was present in the moist cleaning wipes used instead of dry toilet paper. The presented case serves as a basis for a appraisal of the use of this preservative in wet wipes. In addition, the duration of the patch test protocol in children has also been discussed.

摘要

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Contact dermatitis in a child from methlychloroisothiazolinone and methylisothiazolinone in moist wipes.
Pediatr Dermatol. 2014 Mar-Apr;31(2):225-7. doi: 10.1111/j.1525-1470.2012.01804.x. Epub 2012 Jul 2.
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[Peri-anal allergic contact eczema with dyshidrotic eczema of the hands due to the use of Kathon CG moist toilet wipes].[因使用卡松CG湿厕纸导致肛周过敏性接触性皮炎伴手部汗疱疹]
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Allergic contact dermatitis to methylisothiazolinone: exposure from baby wipes causing hand dermatitis.对甲基异噻唑啉酮的过敏性接触性皮炎:婴儿湿巾导致手部皮炎的接触暴露。
Australas J Dermatol. 2013 Nov;54(4):264-7. doi: 10.1111/ajd.12062. Epub 2013 May 29.
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Isothiazolinone preservative as important contact allergen in cosmetics.异噻唑啉酮防腐剂是化妆品中重要的接触性过敏原。
Derm Beruf Umwelt. 1987 Sep-Oct;35(5):169-73.
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[Replacement of Kathon CG by Euxyl K 400 in cosmetics; from the frying pan into the fire?].[化妆品中用优赛林K 400替代凯松CG;才出虎穴,又入狼窝?]
Ned Tijdschr Geneeskd. 1992 Mar 21;136(12):587-9.
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The hazards of moist toilet paper: allergy to the preservative methylchloroisothiazolinone/methylisothiazolinone.湿厕纸的危害:对防腐剂甲基氯异噻唑啉酮/甲基异噻唑啉酮过敏。
Arch Dermatol. 2010 Aug;146(8):886-90. doi: 10.1001/archdermatol.2010.114. Epub 2010 Jun 21.
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Multicentre patch testing with methylisothiazolinone by the European Environmental and Contact Dermatitis Research Group.欧洲环境与接触性皮炎研究小组对甲基异噻唑啉酮进行的多中心斑贴试验。
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[Contact allergy to Kathon CG].对凯松CG的接触性过敏
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Allergic contact dermatitis from Kathon CG in moist toilet paper.湿厕纸中卡松CG引起的变应性接触性皮炎
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Allergic contact dermatitis caused by methylisothiazolinone from different sources, including 'mislabelled' household wet wipes.由不同来源的甲基异噻唑啉酮引起的过敏性接触性皮炎,包括“标签错误”的家用湿纸巾。
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