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动脉高血压与肩袖撕裂的相关性:对肩袖撕裂大小的影响。

The association between arterial hypertension and rotator cuff tear: the influence on rotator cuff tear sizes.

机构信息

Department of Orthopaedic and Traumatology, University of Rome Sapienza, Rome, Italy.

出版信息

J Shoulder Elbow Surg. 2013 Feb;22(2):229-32. doi: 10.1016/j.jse.2012.05.023. Epub 2012 Jun 27.

Abstract

BACKGROUND

This study was conducted to establish whether hypertension increases the risk of occurrence of rotator cuff tear and influences its size.

MATERIALS AND METHODS

A case-control design was used. We studied 408 consecutive patients (228 men, 180 women) who underwent arthroscopic rotator cuff repair. Tear size was determined during surgery. The control group included 201 individuals. For the study purpose, participants were divided into 2 groups by presence or absence of hypertension. We applied a logistic regression model to investigate if hypertension affects the risk of cuff tear. A multinomial logistic regression model was applied to explore the association between hypertension and tear size. We used the analysis of covariance method to determine if the duration of hypertension influences the severity of the tear; finally, we compared mean duration of antihypertensive therapy in patients with small, large, and massive tears. All analyses were adjusted for age and sex.

RESULTS

Hypertension was associated with a 2-fold higher risk of tear occurrence (odds ratio [OR], 2.05; 95% confidence interval [CI], 41-2.98). No association was detected between hypertension and the probability of a small tear (OR, 0.63, 95% CI, 0.33-1.19). Hypertensive individuals were 2 times more likely to experience large tear (OR, 02.09; 95% CI, 1.39-3.16) and 4 times more likely to experience massive tear (OR, 04.30; 95% CI, 2.44-7.58) than normotensive individuals. Mean duration of antihypertensive therapy significantly increased from small tear (1.08 years) to large tear (3.20 years) to massive tear (6.34 years) patients (analysis of covariance: F((2,403)) = 16.357, P = 1.48 × 10(-7)).

CONCLUSIONS

Our data provide evidence that hypertension is a significant risk factor for the occurrence and severity of rotator cuff tears.

摘要

背景

本研究旨在探讨高血压是否会增加肩袖撕裂的发生风险,并影响其严重程度。

材料与方法

采用病例对照设计。我们研究了 408 例连续接受关节镜下肩袖修复的患者(男 228 例,女 180 例)。术中确定撕裂大小。对照组包括 201 人。为了研究目的,根据是否存在高血压将参与者分为两组。我们应用逻辑回归模型来探讨高血压是否会影响肩袖撕裂的风险。应用多项逻辑回归模型来探讨高血压与撕裂大小之间的关系。我们应用协方差分析方法来确定高血压持续时间是否会影响撕裂的严重程度;最后,我们比较了小、大、巨大撕裂患者的降压治疗平均持续时间。所有分析均调整了年龄和性别因素。

结果

高血压与撕裂发生的风险增加 2 倍相关(比值比 [OR],2.05;95%置信区间 [CI],41-2.98)。高血压与小撕裂(OR,0.63;95%CI,0.33-1.19)发生的概率之间无相关性。高血压患者发生大撕裂的风险增加 2 倍(OR,02.09;95%CI,1.39-3.16),发生巨大撕裂的风险增加 4 倍(OR,04.30;95%CI,2.44-7.58)。与非高血压患者相比。降压治疗的平均持续时间从小撕裂(1.08 年)到大撕裂(3.20 年)再到巨大撕裂(6.34 年)患者显著增加(协方差分析:F((2,403)) = 16.357,P = 1.48×10(-7))。

结论

我们的数据提供了证据表明,高血压是肩袖撕裂发生和严重程度的一个重要危险因素。

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