Addiction Research Institute, Budapest, Hungary.
Psychiatry Res. 2012 Dec 30;200(2-3):719-23. doi: 10.1016/j.psychres.2012.06.005. Epub 2012 Jun 29.
The objective of this study was to investigate trait-aggression, depression and suicidal behavior of drug dependent patients with and without ADHD symptoms. The cross sectional survey was conducted in outpatient drug centers in Hungary. The Adult Self-Report Scale (ASRS), the Buss-Perry Aggression Questionnaire (AQ), the European Version of the ADolescent Assessment Dialogue (EuroADAD), and the Beck Depression Inventory (BDI) were used for measures. GLM analyses, adjusting for age and gender, indicated that patients who screened positive for ADHD (ADHD+ group) had significantly higher severity of overall trait aggression, as well as physical and verbal aggression than patients who did not (ADHD negative group). The highest severity of aggression was observed when the ADHD+ status co-occurred with heroin use, while the lowest severity of aggression was detected when ADHD- status co-occurred with the use of marijuana. ADHD+ patients showed a marked increase in depression symptoms, suicidal ideation, suicidal attempts as well as self-injuries associated with suicidal attempts. Considering the substantial costs of aggression and suicide from a societal perspective and from the point of view of the individual sufferer, our results highlight the importance of the diagnostic investigation of ADHD in the treatment of drug dependent patients.
本研究旨在调查伴有和不伴有注意缺陷多动障碍(ADHD)症状的药物依赖患者的特质性攻击行为、抑郁和自杀行为。该横断面研究在匈牙利的门诊药物中心进行。采用成人自评量表(ASRS)、Buss-Perry 攻击问卷(AQ)、欧洲青少年评估对话(EuroADAD)和贝克抑郁量表(BDI)进行评估。GLM 分析,调整年龄和性别,表明对 ADHD 筛查呈阳性的患者(ADHD+组)的总体特质攻击严重程度,以及身体和言语攻击严重程度均明显高于未筛查呈阳性的患者(ADHD-组)。当 ADHD+状态与海洛因使用共现时,观察到最高的攻击严重程度,而当 ADHD-状态与大麻使用共现时,观察到最低的攻击严重程度。ADHD+患者的抑郁症状、自杀意念、自杀企图以及与自杀企图相关的自我伤害明显增加。考虑到从社会角度和从个体患者的角度来看,攻击和自杀的巨大成本,我们的研究结果强调了在治疗药物依赖患者时对 ADHD 进行诊断性调查的重要性。