Service de Bactériologie-Hygiène hospitalière, CHU Nantes, 9 quai Moncousu, 44093 Nantes Cedex 01, France.
Diagn Microbiol Infect Dis. 2012 Sep;74(1):95-7. doi: 10.1016/j.diagmicrobio.2012.05.023. Epub 2012 Jun 28.
We investigated the clinical and microbiological epidemiology of AmpC plasmidic cephalosporinases (pAmpC) in Klebsiella pneumoniae strains resistant to ceftazidime, during a 3-year period (2007-2009). Among 1505 K. pneumoniae, 7 were pAmpC producers. Molecular characterization revealed the spread of a ST37 strain producing DHA-1 within intensive care units and the diffusion of the same plasmid among unrelated strains.
我们研究了在对头孢他啶耐药的肺炎克雷伯菌菌株中,AmpC 质粒头孢菌素酶(pAmpC)的临床和微生物流行病学,研究时间为 3 年(2007-2009 年)。在 1505 株肺炎克雷伯菌中,有 7 株为 pAmpC 产生菌。分子特征表明,产 DHA-1 的 ST37 菌株在重症监护病房中传播,同一质粒在无关菌株中扩散。