Barajas-López Juan de Dios, Blanco Nicolás E, Strand Åsa
Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, S-901 87 Umeå, Sweden.
Biochim Biophys Acta. 2013 Feb;1833(2):425-37. doi: 10.1016/j.bbamcr.2012.06.020. Epub 2012 Jun 27.
The presence of genes encoding organellar proteins in both the nucleus and the organelle necessitates tight coordination of expression by the different genomes, and this has led to the evolution of sophisticated intracellular signaling networks. Organelle-to-nucleus signaling, or retrograde control, coordinates the expression of nuclear genes encoding organellar proteins with the metabolic and developmental state of the organelle. Complex networks of retrograde signals orchestrate major changes in nuclear gene expression and coordinate cellular activities and assist the cell during plant development and stress responses. It has become clear that, even though the chloroplast depends on the nucleus for its function, plastid signals play important roles in an array of different cellular processes vital to the plant. Hence, the chloroplast exerts significant control over the running of the cell. This article is part of a Special Issue entitled: Protein Import and Quality Control in Mitochondria and Plastids.
细胞核和细胞器中都存在编码细胞器蛋白的基因，这就需要不同基因组对基因表达进行紧密协调，进而导致了复杂的细胞内信号网络的进化。细胞器到细胞核的信号传递，即逆行调控，可根据细胞器的代谢和发育状态来协调编码细胞器蛋白的核基因的表达。复杂的逆行信号网络精心安排核基因表达的重大变化，协调细胞活动，并在植物发育和应激反应过程中协助细胞。显而易见的是，尽管叶绿体的功能依赖于细胞核，但质体信号在植物至关重要的一系列不同细胞过程中发挥着重要作用。因此，叶绿体对细胞的运转有着重大控制作用。本文是名为《线粒体和质体中的蛋白质导入与质量控制》特刊的一部分。
