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生物学和医学中的线粒体。

Mitochondria in biology and medicine.

机构信息

Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.

出版信息

Mitochondrion. 2012 Jul;12(4):472-6. doi: 10.1016/j.mito.2012.06.008. Epub 2012 Jun 30.

DOI:10.1016/j.mito.2012.06.008
PMID:22750136
Abstract

Ever since the first diagnosis of a mitochondrial disease in 1959 (Ernster et al., 1959), the interest for mitochondrial cytopathies has continued to increase. Originally it was believed that the condition was very rare and primarily effected high-energy requiring tissues resulting in a select few pathologies (Luft, 1994). Since 1959, the understanding of mitochondrial cytopathies has evolved immensely and mitochondrial cytopathies are now known to be the largest group of metabolic diseases and to be resulting in a wide variety of pathologies. "Mitochondria in Biology and Medicine" was the title of the first annual conference of Society of Mitochondrial Research and Medicine - India. The conference was organized by A. S. Sreedhar, Keshav Singh and Kumarasamy Thangaraj, and was held at The Centre for Cellular and Molecular Biology (CCMB) Hyderabad, India, during 9-10 December 2011. The conference featured talks from internationally renowned scientists within the field of mitochondrial research and offered both students and fellow researchers a comprehensive update to the newest research within the field. This paper summarizes key outcomes of the presentations.

摘要

自 1959 年首次诊断出一种线粒体疾病(Ernster 等人,1959 年)以来,人们对线粒体细胞病变的兴趣不断增加。最初,人们认为这种情况非常罕见,主要影响高能量需求的组织,导致少数几种病理学(Luft,1994 年)。自 1959 年以来,对线粒体细胞病变的认识有了很大的发展,线粒体细胞病变现在被认为是最大的代谢疾病群体,并导致各种病理学。“生物学和医学中的线粒体”是线粒体研究和医学学会的第一次年度会议的标题-印度。该会议由 A.S.Sreedhar、Keshav Singh 和 Kumarasamy Thangaraj 组织,于 2011 年 12 月 9 日至 10 日在印度海得拉巴的细胞和分子生物学中心(CCMB)举行。会议邀请了国际知名的线粒体研究领域的科学家进行演讲,为学生和研究人员提供了该领域最新研究的综合最新信息。本文总结了演讲的主要成果。

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