Ross J, Abate M A
Pharmacy Service (119), Louis A. Johnson Veterans Affairs Medical Center, Clarksburg, WV 26301.
DICP. 1990 Nov;24(11):1050, 1053. doi: 10.1177/106002809002401104.
Staphylococcus aureus and Staphylococcus epidermidis are organisms that frequently cause conjunctivitis or blepharoconjunctivitis. We describe a patient with methicillin-resistant S. aureus and S. epidermidis conjunctivitis who was treated successfully using an extemporaneously prepared topical ophthalmic solution of vancomycin hydrochloride 31 mg/mL. Studies describing the preparation, stability, and comfort of this solution, as well as reports pertaining to efficacy, are reviewed. Controlled clinical trials evaluating the safety and efficacy of vancomycin ophthalmic solution have not yet been performed.
金黄色葡萄球菌和表皮葡萄球菌是经常引起结膜炎或睑结膜炎的微生物。我们描述了一名患有耐甲氧西林金黄色葡萄球菌和表皮葡萄球菌性结膜炎的患者,其使用临时配制的31毫克/毫升盐酸万古霉素局部滴眼液成功治愈。本文回顾了描述该溶液的配制、稳定性和舒适度的研究,以及有关疗效的报告。尚未进行评估万古霉素滴眼液安全性和有效性的对照临床试验。