Department of Colorectal Surgery, Digestive Disease Center-A30, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Surg Endosc. 2010 Aug;24(8):2039-43. doi: 10.1007/s00464-010-0900-x. Epub 2010 Feb 21.
Concerns about prolonged postoperative recovery may detract surgeons from offering colectomy to patients older than 80 years. The adoption of a minimally invasive approach may help to counter these beliefs, but concerns remain as to whether these patients can tolerate a pneumoperitoneum. This study compared outcomes after laparoscopic colectomy (LC) and open colectomy (OC) for patients older than 80 years.
From a prospectively maintained database, 97 patients undergoing elective LC between 1994 and 2008 were identified and matched 1:1 to OC patients for age, gender, year of surgery, extent of resection, proximal diversion, American Society of Anesthesiology score, and body mass index. Short-term outcomes including postoperative mortality, morbidity, and discharge status were assessed.
The LC and OC patients were similar for the matched characteristics. Their mean age was 82.8 years (range, 80-94 years). The conversion rate for the LC patients was 14.4%. The OC group had a higher proportion of cancer patients (93.8% vs. 59.8%; P = 0.001). The discharge status for the LC and OC patients was similar, and most patients were discharged home without assistance (63.9% vs. 62.9%; P = 0.88). The median hospital stay was significantly shorter for LC (6 days; range, 1-67 days) than for OC (7 days; range, 2-53 days; P = 0.001). The 30-day postoperative complications (OC, 43.3% vs. LC, 37.1%; P = 0.38), reoperations (OC, 5.2% vs. LC, 4.1%; P = 0.73), and readmissions (OC, 6.2% vs. LC, 9.3%; P = 0.41) were similar. The overall mortality rate was 5.2% and similar between the two groups.
Complications and other outcomes are similar for LC and OC, and the earlier recovery associated with LC, as evidenced by a shorter hospital stay, may encourage a wider adoption of LC for patients older than 80 years.
对于术后恢复时间较长的担忧可能会使外科医生不愿为 80 岁以上的患者进行结肠切除术。采用微创方法可能有助于克服这些担忧,但对于这些患者是否能够耐受气腹仍存在担忧。本研究比较了腹腔镜结肠切除术(LC)和开腹结肠切除术(OC)治疗 80 岁以上患者的结果。
从一个前瞻性维护的数据库中,确定了 1994 年至 2008 年间接受择期 LC 的 97 例患者,并按年龄、性别、手术年份、切除范围、近端分流、美国麻醉医师协会评分和体重指数与 OC 患者进行 1:1 匹配。评估了短期结果,包括术后死亡率、发病率和出院情况。
LC 和 OC 患者在匹配特征方面相似。他们的平均年龄为 82.8 岁(范围为 80-94 岁)。LC 患者的转化率为 14.4%。OC 组癌症患者比例较高(93.8% vs. 59.8%;P = 0.001)。LC 和 OC 患者的出院情况相似,大多数患者无需帮助即可出院回家(63.9% vs. 62.9%;P = 0.88)。LC 的中位住院时间明显短于 OC(6 天;范围为 1-67 天),而 OC 的中位住院时间为 7 天(范围为 2-53 天;P = 0.001)。30 天术后并发症(OC:43.3% vs. LC:37.1%;P = 0.38)、再次手术(OC:5.2% vs. LC:4.1%;P = 0.73)和再入院(OC:6.2% vs. LC:9.3%;P = 0.41)相似。总死亡率为 5.2%,两组相似。
LC 和 OC 的并发症和其他结果相似,LC 术后恢复较快,这可能会鼓励更广泛地为 80 岁以上的患者采用 LC。