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腹腔镜结肠切除术对 80 岁以上老年人是安全的,并可显著缩短住院时间。

Laparoscopic colectomy is safe and leads to a significantly shorter hospital stay for octogenarians.

机构信息

Department of Colorectal Surgery, Digestive Disease Center-A30, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Surg Endosc. 2010 Aug;24(8):2039-43. doi: 10.1007/s00464-010-0900-x. Epub 2010 Feb 21.

Abstract

BACKGROUND

Concerns about prolonged postoperative recovery may detract surgeons from offering colectomy to patients older than 80 years. The adoption of a minimally invasive approach may help to counter these beliefs, but concerns remain as to whether these patients can tolerate a pneumoperitoneum. This study compared outcomes after laparoscopic colectomy (LC) and open colectomy (OC) for patients older than 80 years.

METHODS

From a prospectively maintained database, 97 patients undergoing elective LC between 1994 and 2008 were identified and matched 1:1 to OC patients for age, gender, year of surgery, extent of resection, proximal diversion, American Society of Anesthesiology score, and body mass index. Short-term outcomes including postoperative mortality, morbidity, and discharge status were assessed.

RESULTS

The LC and OC patients were similar for the matched characteristics. Their mean age was 82.8 years (range, 80-94 years). The conversion rate for the LC patients was 14.4%. The OC group had a higher proportion of cancer patients (93.8% vs. 59.8%; P = 0.001). The discharge status for the LC and OC patients was similar, and most patients were discharged home without assistance (63.9% vs. 62.9%; P = 0.88). The median hospital stay was significantly shorter for LC (6 days; range, 1-67 days) than for OC (7 days; range, 2-53 days; P = 0.001). The 30-day postoperative complications (OC, 43.3% vs. LC, 37.1%; P = 0.38), reoperations (OC, 5.2% vs. LC, 4.1%; P = 0.73), and readmissions (OC, 6.2% vs. LC, 9.3%; P = 0.41) were similar. The overall mortality rate was 5.2% and similar between the two groups.

CONCLUSION

Complications and other outcomes are similar for LC and OC, and the earlier recovery associated with LC, as evidenced by a shorter hospital stay, may encourage a wider adoption of LC for patients older than 80 years.

摘要

背景

对于术后恢复时间较长的担忧可能会使外科医生不愿为 80 岁以上的患者进行结肠切除术。采用微创方法可能有助于克服这些担忧,但对于这些患者是否能够耐受气腹仍存在担忧。本研究比较了腹腔镜结肠切除术(LC)和开腹结肠切除术(OC)治疗 80 岁以上患者的结果。

方法

从一个前瞻性维护的数据库中,确定了 1994 年至 2008 年间接受择期 LC 的 97 例患者,并按年龄、性别、手术年份、切除范围、近端分流、美国麻醉医师协会评分和体重指数与 OC 患者进行 1:1 匹配。评估了短期结果,包括术后死亡率、发病率和出院情况。

结果

LC 和 OC 患者在匹配特征方面相似。他们的平均年龄为 82.8 岁(范围为 80-94 岁)。LC 患者的转化率为 14.4%。OC 组癌症患者比例较高(93.8% vs. 59.8%;P = 0.001)。LC 和 OC 患者的出院情况相似,大多数患者无需帮助即可出院回家(63.9% vs. 62.9%;P = 0.88)。LC 的中位住院时间明显短于 OC(6 天;范围为 1-67 天),而 OC 的中位住院时间为 7 天(范围为 2-53 天;P = 0.001)。30 天术后并发症(OC:43.3% vs. LC:37.1%;P = 0.38)、再次手术(OC:5.2% vs. LC:4.1%;P = 0.73)和再入院(OC:6.2% vs. LC:9.3%;P = 0.41)相似。总死亡率为 5.2%,两组相似。

结论

LC 和 OC 的并发症和其他结果相似,LC 术后恢复较快,这可能会鼓励更广泛地为 80 岁以上的患者采用 LC。

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