Rossi Mark A, Yin Henry H
Department of Psychology and Neuroscience, Center for Cognitive Neuroscience, Duke University, Durham, North Carolina, USA.
Curr Protoc Neurosci. 2012 Jul;Chapter 8:Unit 8.29. doi: 10.1002/0471142301.ns0829s60.
Habit formation refers to the process by which goal-directed behavior becomes automatized and less sensitive to changes in the value of the goal. It has clear relevance for our understanding of skill learning and addiction. Recent studies have begun to reveal the neural substrates underlying this process. This unit summarizes what is known about the experimental methods used, and provides a protocol for generating and assessing habit formation in mice.
习惯形成是指目标导向行为变得自动化且对目标价值变化的敏感度降低的过程。它与我们对技能学习和成瘾的理解密切相关。最近的研究已开始揭示这一过程背后的神经基础。本单元总结了关于所使用实验方法的已知信息,并提供了一种在小鼠中产生和评估习惯形成的方案。