Pipestone Veterinary Clinic, Pipestone, MN 56164, USA.
Viruses. 2012 May;4(5):654-62. doi: 10.3390/v4050654. Epub 2012 Apr 26.
Airborne transmission of porcine reproductive and respiratory syndrome virus (PRRSV) is a risk factor for the infection of susceptible populations. Therefore, a long‑term sustainability study of air filtration as a means to reduce this risk was conducted. Participating herds (n = 38) were organized into 4 independent cohorts and the effect of air filtration on the occurrence of new PRRSV infections was analyzed at 3 different levels from September 2008 to January 2012 including the likelihood of infection in contemporary filtered and non-filtered herds, the likelihood of infection before and after implementation of filtration and the time to failure in filtered and non-filtered herds. Results indicated that new PRRSV infections in filtered breeding herds were significantly lower than in contemporary non-filtered control herds (P < 0.01), the odds for a new PRRSV infection in breeding herds before filtration was 7.97 times higher than the odds after filtration was initiated (P < 0.01) and the median time to new PRRSV infections in filtered breeding herds of 30 months was significantly longer than the 11 months observed in non-filtered herds (P < 0.01). In conclusion, across all 3 levels of analysis, the long-term effect of air filtration on reducing the occurrence of new PRRSV infections in the study population was demonstrated.
猪繁殖与呼吸综合征病毒（PRRSV）的空气传播是易感人群感染的一个风险因素。因此，进行了一项空气过滤长期可持续性研究，以降低这种风险。参与的牛群（n=38）分为 4 个独立的队列，从 2008 年 9 月到 2012 年 1 月，在 3 个不同水平上分析了空气过滤对新 PRRSV 感染发生的影响，包括当代过滤和非过滤牛群感染的可能性、过滤实施前后感染的可能性以及过滤和非过滤牛群失效的时间。结果表明，过滤繁殖牛群中新的 PRRSV 感染明显低于当代非过滤对照牛群（P<0.01），过滤前繁殖牛群中新的 PRRSV 感染的可能性是过滤后开始时的 7.97 倍（P<0.01），过滤繁殖牛群中新的 PRRSV 感染的中位数时间为 30 个月，明显长于非过滤牛群的 11 个月（P<0.01）。总之，在所有 3 个分析水平上，空气过滤对降低研究人群中新 PRRSV 感染发生的长期效果得到了证明。
