Hammer K H, Klingberg F
Paul Flechsig Institute for Brain Research, Department of Neurophysiology, Karl Marx University, Leipzig, GDR.
Biomed Biochim Acta. 1990;49(6):499-503.
Active avoidance of eighteen adult male hooded rats was investigated in an Y-maze and a jump test before and after small symmetric lesions of the median raphe nucleus (n. centralis superior, CES). Formation of conditioned avoidance responses (CAR) was impossible without preoperative experience. Retention of preoperatively learnt CAR was almost zero after lesions. Relearning was strongly delayed but possible in the jump test, however, not in the Y-maze. CES rats did not reach criterion in brightness discrimination. On the other hand, their spontaneous behaviour in the open field remained unchanged.
在中缝正中核（中央上核，CES）进行小的对称损伤前后，在Y型迷宫和跳跃试验中对18只成年雄性带帽大鼠的主动回避行为进行了研究。没有术前经验就不可能形成条件回避反应（CAR）。损伤后，术前习得的CAR的保持率几乎为零。重新学习受到强烈延迟，但在跳跃试验中是可能的，然而，在Y型迷宫中则不可能。CES大鼠在亮度辨别方面未达到标准。另一方面，它们在旷场中的自发行为保持不变。
