Allergy and Immunology Clinic, Pulmonary Institute, Rabin Medical Center, Petah Tiqva, Israel.
Acta Paediatr. 2012 Oct;101(10):1083-8. doi: 10.1111/j.1651-2227.2012.02776.x. Epub 2012 Jul 24.
To investigate the prevalence of reported food allergy and its association with atopic diseases and asthma severity among Jewish and Arab adolescents.
The self-report questionnaire of the International Study of Asthma and Allergies in Childhood (ISAAC) was administered to adolescents aged 13-14 years from randomly selected junior high schools in Israel. Questions regarding food allergy were added.
A total of 11 171 questionnaires were available for analysis. Food allergy was reported by 3.6% of participants: 1.9% milk, 0.6% egg, 0.6% peanut and 0.4% sesame. On multivariate analysis, food allergy was strongly associated with current asthma (OR, 2.5; 95% CI, 1.8-3.3), atopic eczema (OR, 3.2; 95% CI, 2.4-4.3) and allergic rhinitis (OR, 2.4; 95% CI, 1.8-3.1). Arabs were significantly more allergic to peanut (OR, 2.5; 95% CI, 1.5-4.1), egg (OR, 3.5; 95% CI, 2.1-5.9) and sesame (OR, 2.3; 95% CI, 1.2-4.5) than Jews, and less allergic to milk (OR, 0.6; 95% CI, 0.4-0.9). Asthmatic subjects with food allergy had significantly more parameters of severe asthma than those without food allergy (p < 0.001).
The prevalence of allergy to specific foods differs between Jews and Arabs. Asthmatic adolescents with food allergy report more severe asthma than those without food allergy.
调查报告的食物过敏的流行率及其与犹太人和阿拉伯青少年特应性疾病和哮喘严重程度的关系。
采用国际儿童哮喘和过敏研究（ISAAC）的自我报告问卷对以色列随机选择的初中 13-14 岁青少年进行调查。增加了有关食物过敏的问题。
共分析了 11171 份问卷。3.6%的参与者报告有食物过敏：1.9%牛奶，0.6%鸡蛋，0.6%花生和 0.4%芝麻。多变量分析显示，食物过敏与当前哮喘（OR，2.5；95%CI，1.8-3.3）、特应性皮炎（OR，3.2；95%CI，2.4-4.3）和过敏性鼻炎（OR，2.4；95%CI，1.8-3.1）密切相关。阿拉伯人对花生（OR，2.5；95%CI，1.5-4.1）、鸡蛋（OR，3.5；95%CI，2.1-5.9）和芝麻（OR，2.3；95%CI，1.2-4.5）过敏的比例明显高于犹太人，对牛奶（OR，0.6；95%CI，0.4-0.9）过敏的比例明显低于犹太人。有食物过敏的哮喘患者比无食物过敏的哮喘患者有更多严重哮喘的参数（p<0.001）。
犹太人和阿拉伯人对特定食物的过敏发生率不同。有食物过敏的哮喘青少年比无食物过敏的哮喘青少年报告更严重的哮喘。
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