儿童哮喘与食物过敏
Pediatric Asthma and Food Allergy.
机构信息
Department of Pediatrics, Anhui Provincial Hospital, No. 17, Lu Jiang Road, Hefei, 230001, China.
Department of Pediatrics, The Affiliated Provincial Hospital of Anhui Medical University, Hefei, China.
出版信息
Indian J Pediatr. 2017 Aug;84(8):585-590. doi: 10.1007/s12098-017-2326-0. Epub 2017 Apr 7.
OBJECTIVE
To quantitatively summarize the evidence from observational studies on the relation between pediatric asthma and food allergy.
METHODS
A literature search was conducted in Medline and EMBASE (August 2016). Two independent reviewers appraised the studies and extracted the estimates of interest. Methodological quality of the included studies was assessed using National Heart Lung and Blood Institute (NHLBI) Quality Assessment Tools. Data were pooled using random-effects meta-analysis.
RESULTS
A total of 32 relevant studies were identified but only 8 studies met the inclusion criteria. Using random-effect model, food allergy showed strong association with asthma in children (OR = 2.87 [95% CI: 2.05-4.00]; P < 0.0001).
CONCLUSIONS
This study suggested that food allergy is associated with an increased risk of asthma in children.
目的
定量总结观察性研究中关于儿童哮喘与食物过敏之间关系的证据。
方法
在 Medline 和 EMBASE 中进行了文献检索（2016 年 8 月）。两名独立的审查员评估了研究并提取了感兴趣的估计值。使用国家心肺血液研究所（NHLBI）质量评估工具评估纳入研究的方法学质量。使用随机效应荟萃分析对数据进行汇总。
结果
共确定了 32 项相关研究，但只有 8 项研究符合纳入标准。使用随机效应模型，食物过敏与儿童哮喘有很强的关联（OR=2.87 [95% CI：2.05-4.00]；P<0.0001）。
结论
这项研究表明，食物过敏与儿童哮喘的风险增加有关。
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