Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois, 60611, USA.
Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, California, USA.
Curr Allergy Asthma Rep. 2020 Feb 14;20(2):6. doi: 10.1007/s11882-020-0898-7.
In recent decades, food allergy has become an increasing concern for families, clinicians, and policymakers. This review aims to summarize what is currently known about the epidemiology and population-level burden of IgE-mediated food allergy, including its effects on quality of life.
Prevalence surveys, healthcare utilization data, and findings from longitudinal cohort studies across the globe indicate that food allergy imposes a growing societal burden. Worryingly, recent data indicate that food allergies may be more prevalent among adult populations than previously acknowledged, with many reported cases of adult-onset allergies. While it remains unclear how much of the current population-level burden of disease results from true, IgE-mediated allergy, as much epidemiological data does not incorporate clinical confirmation of disease prevalence-it is clear that affected individuals suffer impairments in their quality of life and incur substantial economic costs-beyond the physical health burden imposed by anaphylaxis.
近几十年来，食物过敏引起了家庭、临床医生和政策制定者的广泛关注。本文旨在总结目前已知的 IgE 介导的食物过敏的流行病学和人群负担，包括其对生活质量的影响。
全球范围内的流行调查、医疗保健利用数据以及纵向队列研究的结果表明，食物过敏给社会带来的负担日益加重。令人担忧的是，最近的数据表明，食物过敏在成年人群体中的发病率可能高于先前的认识，许多报告的过敏病例为成人发病。虽然目前尚不清楚有多少疾病的人群负担是真正的 IgE 介导的过敏引起的，因为许多流行病学数据并未将疾病流行的临床确认纳入其中，但很明显，受影响的个体的生活质量受损，并带来巨大的经济成本——除了过敏反应带来的身体健康负担。
