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并非所有首发精神病都是相同的:精神分裂症谱系病例中基本自我干扰更大的初步证据。

Not all first-episode psychosis is the same: preliminary evidence of greater basic self-disturbance in schizophrenia spectrum cases.

机构信息

Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, Victoria, Australia.

出版信息

Early Interv Psychiatry. 2013 May;7(2):200-4. doi: 10.1111/j.1751-7893.2012.00381.x. Epub 2012 Jul 3.

Abstract

AIM

Disturbance in the basic sense of self has previously been found to characterize schizophrenia spectrum disorders and to predict onset of psychosis in the ultra-high-risk population. The current study examined basic self-disturbance in a first-episode psychosis (FEP) population. We hypothesized that basic self-disturbance would be more prominent in cases with a schizophrenia spectrum disorder compared to those with other psychoses.

METHOD

Sixteen FEP patients from Orygen Youth Health, Melbourne, were recruited to the study. Participants were assessed using the Examination of Anomalous Self-Experience and the Structured Clinical Interview for DSM-IV.

RESULTS

Basic self-disturbance scores were significantly higher in patients with a schizophrenia spectrum diagnosis (n = 8) compared to patients with other psychotic diagnoses (n = 8).

CONCLUSIONS

The findings are consistent with previous work indicating that the disturbance of the basic sense of self is more characteristic of schizophrenia spectrum psychosis than other psychoses. This may have implications for early diagnosis, clinical formulation and intervention.

摘要

目的

先前的研究发现,基本自我意识障碍的特征在于精神分裂症谱系障碍,并可预测超高危人群的精神病发作。本研究旨在检查首发精神病(FEP)人群中的基本自我障碍。我们假设,与其他精神病相比,具有精神分裂症谱系障碍的病例中基本自我障碍更为突出。

方法

本研究招募了来自墨尔本 Orygen 青年健康中心的 16 名 FEP 患者。参与者使用异常自我体验检查和 DSM-IV 结构化临床访谈进行评估。

结果

具有精神分裂症谱系诊断的患者(n=8)的基本自我障碍评分明显高于具有其他精神病诊断的患者(n=8)。

结论

这些发现与先前的研究结果一致,表明基本自我意识障碍更具精神分裂症谱系精神病的特征,而非其他精神病。这可能对早期诊断、临床制定和干预具有重要意义。

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