Raballo Andrea, Parnas Josef
Danish National Research Foundation, Center for Subjectivity Research, Department of Psychiatry, Psychiatric Center Hvidovre, University of Copenhagen, Copenhagen, Denmark.
J Nerv Ment Dis. 2012 Jul;200(7):577-83. doi: 10.1097/NMD.0b013e31825bfb41.
A growing body of evidence points to the clinical and heuristic value of anomalous subjective experiences (ASEs) for the characterization of schizophrenia spectrum vulnerability and early detection purposes. In particular, a subgroup of ASEs, entailing basic disorders of self-awareness (self-disorders [SDs]), has been shown to constitute a core feature of both clinically overt and latent (schizotaxic) spectrum phenotypes. However, a major limitation for the translational implementation of this research evidence has been a lack of assessment tools capable of encompassing the clinical richness of SDs. Here, we present the initial normative data and psychometric properties of a newly developed instrument (Examination of Anomalous Self-experience [EASE]), specifically designed to support the psychopathological exploration of SDs in both research and "real world" clinical settings. Our results support the clinical validity of the EASE as a tool for assessing anomalies of self-awareness (SDs) and lend credit to the translational potential of a phenomenological exploration of the subjective experience of vulnerability to schizophrenia.
越来越多的证据表明，异常主观体验（ASEs）对于精神分裂症谱系易感性的特征描述和早期检测具有临床及启发价值。特别是，ASEs的一个亚组，即涉及自我意识基本障碍（自我障碍[SDs]）的亚组，已被证明是临床显性和潜在（分裂型）谱系表型的核心特征。然而，该研究证据转化应用的一个主要限制是缺乏能够涵盖SDs临床丰富性的评估工具。在此，我们展示了一种新开发工具（异常自我体验检查[EASE]）的初始常模数据和心理测量特性，该工具专门设计用于支持在研究和“现实世界”临床环境中对SDs进行心理病理学探索。我们的结果支持EASE作为评估自我意识异常（SDs）工具的临床有效性，并为对精神分裂症易感性主观体验进行现象学探索的转化潜力提供了支持。
