Idika I K, Nwauzoije H C, Uju C N, Ugwuoke C, Ezeokonkwo R C
Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria.
Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria.
Vet Parasitol Reg Stud Reports. 2017 Dec;10:39-42. doi: 10.1016/j.vprsr.2017.07.006. Epub 2017 Jul 22.
Ivermectin is a frequently used anthelmintic in pig production in Nigeria, because it is very effective against a broad range of endo- and ecto-parasites. However, gastrointestinal (GI) nematode infection still remains a major threat in pig production in Enugu state, Nigeria. Hence, the efficacy of ivermectin against GI nematode parasites of pig was evaluated in pig farms located in Nsukka area of Enugu State, using the Faecal egg count reduction test (FECRT). From each of 11 pig farms, 10 randomly selected female pigs were used for the study. Faecal samples were collected per rectum from each of the pigs for analysis, and their individual faecal egg count (FEC) per gram of faeces determined prior to treatment with ivermectine® (1% Ivemectin). A repeat sampling was carried out on the same pigs 12days post treatment (PT) to determine PT FEC. The efficacy of the anthelmintic, was calculated using the formular, FECR (%)=100 X (1-[T2/T1]). The ivermectin produced mean FECR% of 98.36%±0.43% against strongyle eggs and 100% against ascarid and trichurid in the farms. Consequently, at the level of the FECRT, the ivermectin used in this study was effective against GI nematode parasites of pigs in the study area, and no resistance was observed.
伊维菌素是尼日利亚养猪生产中常用的一种驱虫药，因为它对多种体内和体外寄生虫都非常有效。然而，胃肠道（GI）线虫感染仍然是尼日利亚埃努古州养猪生产中的一个主要威胁。因此，在埃努古州Nsukka地区的养猪场，使用粪便虫卵计数减少试验（FECRT）评估了伊维菌素对猪胃肠道线虫寄生虫的疗效。从11个养猪场中，每个猪场随机挑选10头母猪用于该研究。从每头猪的直肠采集粪便样本进行分析，并在使用伊维菌素®（1%伊维菌素）治疗前测定每克粪便中的个体粪便虫卵计数（FEC）。在治疗后12天（PT）对同一批猪进行重复采样，以确定PT FEC。使用公式FECR（%）=100×（1-[T2/T1]）计算驱虫药的疗效。在这些猪场中，伊维菌素对圆线虫卵的平均FECR%为98.36%±0.43%，对蛔虫和鞭虫的FECR为100%。因此，在FECRT水平上，本研究中使用的伊维菌素对研究区域内猪的胃肠道线虫寄生虫有效，且未观察到耐药性。
