Feiz Atiyeh, Arbabzadeh Zavareh Farahnaz, Mohammad Razavi Seyed, Badrian Hamid, Dolatyar Sepideh, Vajihi Mansoureh
Department of Operative Dentistry and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Int J Dent. 2012;2012:156352. doi: 10.1155/2012/156352. Epub 2012 Jun 14.
The aim of the study was to determine and compare the reaction of rat subcutaneous connective tissue to resin composites polymerized with different lights curing and lightening methods. In this in vivo study, 20 mature Wister Albino rats were used. The composite discs, 4 mm in diameter and 2 mm thick, were cured by QTH or LED light curing units with 4 different lightning methods (full power QTH, full power LED, pulse LED, and ramp LED). Five resin composite discs were implanted in each rat, so that 4 of 5 discs for implantation of cured composite discs differently and central one as control without implantation. After sacrificing at 7, 14, 30, and 60 days the inflammatory grade, fibrosis, and necrosis were determined. Freedman and Cochran tests were used to analyze the data using SPSS software ver. 15. The results of the study showed significant differences in inflammation grade and fibrosis among control group and 4 experimental groups at day 14 (P < 0.05). In necrosis, there was no significant difference among 4 groups in different times (P > 0.05). In conclusion, neither the type of light curing units (LED or QTH) nor the lightening methods can affect the grade of inflammatory reaction.
本研究的目的是确定并比较大鼠皮下结缔组织对采用不同光照固化和打光方法聚合的树脂复合材料的反应。在这项体内研究中，使用了20只成年Wister白化大鼠。将直径4毫米、厚2毫米的复合盘用石英卤钨灯（QTH）或发光二极管（LED）光固化装置以4种不同的打光方法（全功率QTH、全功率LED、脉冲LED和斜坡LED）进行固化。每只大鼠植入5个树脂复合盘，其中5个用于植入的固化复合盘中，4个采用不同的固化方式，中间1个作为未植入的对照。在第7、14、30和60天处死大鼠后，确定炎症分级、纤维化和坏死情况。使用SPSS软件15版，采用弗里德曼检验和 Cochr an检验对数据进行分析。研究结果显示，在第14天，对照组和4个实验组之间的炎症分级和纤维化存在显著差异（P < 0.05）。在坏死方面，4组在不同时间没有显著差异（P > 0.05）。总之，无论是光固化装置的类型（LED或QTH）还是打光方法都不会影响炎症反应的程度。
