Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.
Arch Clin Neuropsychol. 2012 Nov;27(7):742-8. doi: 10.1093/arclin/acs060. Epub 2012 Jul 4.
The Montreal Cognitive Assessment (MoCA) is a relatively newly designed test that was developed as a tool to screen patients with mild cognitive problems that are not typically detected by the Mini-Mental State Exam (MMSE). While early research suggests that the MoCA is more sensitive to subtle cognitive impairment than the MMSE, there is concern about potential decreased specificity when using the MoCA. The aim of the present study was to examine the comparative utility of using the MoCA and the MMSE to detect subtle cognitive impairment among a group of 82 middle-aged U.S. military veterans referred for outpatient neuropsychological testing. Using receiver operating characteristic analyses, the MoCA was shown to be a better predictor of subtle cognitive impairment on neuropsychological testing than the MMSE. When using an adjusted cutoff, the MoCA was shown to be more sensitive (i.e., 0.72 vs. 0.52) and nearly as specific as the MMSE (0.75 vs. 0.77).
蒙特利尔认知评估（MoCA）是一种相对较新设计的测试，旨在作为一种工具来筛选轻度认知障碍患者，这些患者通常不会被简易精神状态检查（MMSE）检测到。虽然早期研究表明，MoCA 比 MMSE 更敏感地检测到细微的认知障碍，但人们担心在使用 MoCA 时可能会降低特异性。本研究旨在检查使用 MoCA 和 MMSE 来检测一组 82 名接受门诊神经心理测试的美国中年退伍军人细微认知障碍的比较效用。使用接收者操作特征分析，MoCA 显示在神经心理学测试中是细微认知障碍的更好预测指标，而 MMSE 则不是。当使用调整后的截止值时，MoCA 显示出更高的敏感性（即 0.72 对 0.52），几乎与 MMSE 一样具有特异性（0.75 对 0.77）。
